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The aim of this randomized controlled trial is to compare partial pulpotomy treatments with Biodentine®, calcium hydroxide (CH) and Mineral Trioxide Aggregate (MTA) in cariously exposed asymptomatic young permanent teeth clinically and radiographically for 1 year and evaluate root developments with Image J Software Program. The null hypothesis of this study is Biodentine® will promote healing with high success rates and induce root development more than CH and MTA.
The purpose of this study was to evaluate clinical and radiographical success of three different materials in partial pulpotomy treatment. 50 patients with 54 asymptomatic, cariously exposed young permanent mandibular molar teeth were included to the study. The teeth were randomly divided into three main groups which were; calcium hydroxide, MTA and Biodentine® and finally restorated with stainless steel crowns. Pain, percussion sensitivity, palpation sensitivity of soft tissue around the tooth, root development, presence of lesion, integrity of lamina dura were evaluated clinically and radiographically during 12 months and recorded for each. Also, Image J Program with Turbo-Reg plug in was used for standardization of the radiographs and to determine the increase in root length.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Biodentine | Experimental | Partial pulpotomy treatment with Biodentine |
|
| Calcium Hydroxide | Active Comparator | Partial pulpotomy treatment with Calcium Hydroxide |
|
| Mineral Trioxide Aggregate | Experimental | Partial pulpotomy treatment with Mineral Trioxide Aggregate |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Partial Pulpotomy | Procedure | Partial removal of inflamed pulp tissue in cariously exposed teeth |
|
| Measure | Description | Time Frame |
|---|---|---|
| Root development | Root length measurement in pixels with Image J Software Program | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical Evaluation | Percussion sensitivity evaluation with blunt end of a dental instrument comparing with contralateral or next healthy tooth | 12 months |
| Radiographical Evaluation | Integrity of lamina dura with visual evaluation of radiopaque line around the root using image plate system |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Alev Alacam, DDS, PhD | Gazi University, Faculty of Dentistry, Department of Pediatric Dentistry | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gazi University, Faculty of Dentistry, Department of Pediatric Dentistry | Ankara | 06510 | Turkey (Türkiye) |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Jul 22, 2019 | |
| Reset | Aug 30, 2019 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jul 22, 2019 | Aug 30, 2019 |
| ID | Term |
|---|---|
| D003731 | Dental Caries |
| ID | Term |
|---|---|
| D017001 | Tooth Demineralization |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D057872 | Pulp Capping and Pulpectomy Agents |
| ID | Term |
|---|---|
| D003764 | Dental Materials |
| D001697 | Biomedical and Dental Materials |
| D020313 | Specialty Uses of Chemicals |
| D020164 | Chemical Actions and Uses |
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|
| Pulp Capping Agents | Drug | Biocompatible materials |
|
|
| 12 months |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |