Surgical Stress and Intracorporeal Anastomosis

Intracorporeal Versus Extracorporeal Anastomosis After Laparoscopic Right Colectomy

The short-term advantages of minimally invasive colon resection have been well established in several randomized trials. A major factor in the development of morbidity is the surgical stress response with subsequent increased demand on the patient's reserves and immune competence. Although the advantage in term of stress response of laparoscopic surgery over open surgery has been widely reported, little is known about the role of Intracorporeal anastomosis.

In an attempt to evaluate the surgical stress response after totally laparoscopic right colectomy a comparative study has been designed.

Two surgical procedures will be evaluated:

• Totally laparoscopic right colectomy with intracorporeal anastomosis (Experimental group)
• Laparoscopic assisted right colectomy with extracorporeal anastomosis (Control group).

Inclusion Criteria:

All elective laparoscopic right colectomy for cancer

Exclusion Criteria:

Urgent procedures Immune depressant therapy Immune depressant disease Post-operative Complications