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This is a sample study that will collect biological samples (blood, tumor tissue, ascites, and/or other fluids) from gynecological cancer patients for biomarker research. In addition, the results of the testing done on the samples will be given to the participant's treating physician who may use the information to guide treatment decisions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sample Collection | Experimental | The following samples may be collected during the study:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tumour tissue collection | Procedure | Tumour tissue will be taken from samples already removed from surgery or biopsy or by new tumour biopsies:
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| Measure | Description | Time Frame |
|---|---|---|
| Genomic and immune signatures in terms of progression free survival | Short term (1-2 years) versus long term (5-10 years) survival | 10 years |
| Genomic and immune signatures in terms of overall survival | Short term (1-2 years) versus long term (5-10 years) survival | 10 years |
| Genomic and immune signatures in terms of response to treatments | 10 years | |
| Genomic and immune signatures in terms of resistance to treatments | 10 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Amit Oza, M.D. | Contact | 416-946-2818 | amit.oza@uhn.ca |
| Name | Affiliation | Role |
|---|---|---|
| Amit Oza, M.D. | Princess Margaret Cancer Centre | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Royal Victoria Regional Health Centre | Recruiting | Barrie | Ontario | L4M 6M2 | Canada |
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| Blood sample collection | Procedure | Blood samples will be taken:
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| Ascites Collection | Procedure | Ascites will be collected if paracentesis is required during any of the following time points:
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| Fluid Collection | Procedure | Additional fluid will be collected at any time a procedure for clinical management that involves the drainage of fluid (i.e. thoracentesis, or drainage of cystic lesion) is required. |
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| Juravinski Cancer Centre | Active, not recruiting | Hamilton | Ontario | L8V 5C2 | Canada |
| Kingston Health Sciences Centre | Recruiting | Kingston | Ontario | K7L 2V7 | Canada |
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| London Health Sciences Centre | Recruiting | London | Ontario | Canada |
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| The Ottawa Hospital Cancer Centre | Recruiting | Ottawa | Ontario | K1H 8L6 | Canada |
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| Sunnybrook Health Sciences Centre | Recruiting | Toronto | Ontario | M4N 3M5 | Canada |
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| Princess Margaret Cancer Centre | Recruiting | Toronto | Ontario | M5G 1Z5 | Canada |
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