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| Name | Class |
|---|---|
| ARCAGY/ GINECO GROUP | OTHER |
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While they are documented in patients in remission of testicular cancer, the sequelae of chemotherapy and the impact of the disease and its treatments on the living conditions and QoL of women in remission of rare ovarian cancer remain poorly explored.
The coordinator therefore propose a national 2-step case-control study to evaluate 1) chronic fatigue and QoL and 2) chemotherapy-related sequelae in adult patients in remission of surgery-treated TGMO or TSCS (conservative or not) supplemented with chemotherapy
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Interest group (patients treated with chemotherapy) | Other | Patients will complete several self-questionnaires on living conditions and quality of life. They will also perform a cardiac, pulmonary, auditory and biological assessment |
|
| Patient control group (patients not treated with chemotherapy) | Other | Patients will complete several self-questionnaires on living conditions and quality of life. They will also perform a cardiac, pulmonary, auditory and biological assessment |
|
| Healthy volunteers | Other | Healthy volunteers will complete several self-questionnaires on living conditions and quality of life. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Self-questionnaires of living conditions and quality of life | Other | Patients will complete self-questionnaires of living conditions and quality of life (MFI-20, FACT-G/FACT-O, FACT/COG-NTX, FACT-Cog, HADS, Insomnia Severity Index , International Physical Activity Questionnaire) |
| Measure | Description | Time Frame |
|---|---|---|
| The chronic fatigue by questionnaires | 2 years after surgery | |
| The late sequelae of chemotherapy, particularly cardiovascular and pulmonary disorders, in adult patients in remission of a rare cancer of the ovary treated by surgery, supplemented or not by chemotherapy. | 2 years after surgery | |
| The quality of life by questionnaires | 2 years after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| The fertility monitoring by questionnaires | 2 years after surgery | |
| The symptoms of menopause by questionnaires | 2 years after surgery | |
| Theimpact of cancer and its treatments on the trajectory and professional situation by questionnaires(access to work, professional ambition, financial situation ...); |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Florence JOLY | Centre François Baclesse | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| HEGP | Paris | Paris | France | |||
| Centre Paul Papin |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41382138 | Derived | Dubot C, Ray-Coquard I, Lequesne J, Pautier P, Renaud T, Selle F, Berton-Rigaud D, Frank S, De La Motte Rouge T, Kalbacher E, Provansal M, Blonz C, Orfeuvre H, Alexandre J, Augereau P, Nadeau C, Kurtz JE, Hanvic B, Fresneau B, Ahmed-Lecheheb D, Christy F, Grellard JM, Clarisse B, Gernier F, Joly F. Long-term quality of life in non-epithelial ovarian cancer survivors: TMRG-GINECO-Vivrovaire rare tumors case-control study. BMC Med. 2025 Dec 12;24(1):34. doi: 10.1186/s12916-025-04540-x. |
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Patients and healthy volunteers will complete several self-questionnaires on living conditions and quality of life. Patients will also perform a cardiac, pulmonary, auditory and biological assessment
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|
| Cardiac, pulmonary, auditory and biological assessment | Diagnostic Test | Patients will perform :
|
|
| 2 years after surgery |
| The parental projects by age (≤ 45 years) by questionnaires | 2 years after surgery |
| Angers |
| France |
| CHU Besançon Jean MINJOZ | Besançon | France |
| Institut Bergonié | Bordeaux | France |
| CH Fleyriat | Bourg-en-Bresse | France |
| Centre François Baclesse | Caen | France |
| Centre Jean Perrin | Clermont-Ferrand | France |
| Centre Léon Berard | Lyon | France |
| Institut Paoli Calmettes | Marseille | France |
| Centre Catherine de Sienne | Nantes | France |
| Institut de Cancérologie de l'Ouest | Nantes | France |
| GH Cochin Broca Hôtel-Dieu | Paris | France |
| Hôpital Diaconesses-Croix St Simon | Paris | France |
| Institut Curie, | Paris | France |
| Institut Gustave Roussy | Paris | France |
| CHU Poitiers | Poitiers | France |
| Institut Jean Godinot | Reims | France |
| Institut Rennais de Cancérologie | Rennes | France |
| CHRU Stasbourg Hôpital Civil | Strasbourg | France |
| ID | Term |
|---|---|
| D009373 | Neoplasms, Germ Cell and Embryonal |
| D018312 | Sex Cord-Gonadal Stromal Tumors |
| ID | Term |
|---|---|
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D018309 | Neoplasms, Gonadal Tissue |
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| ID | Term |
|---|---|
| D011788 | Quality of Life |
| ID | Term |
|---|---|
| D006304 | Health Status |
| D003710 | Demography |
| D015991 | Epidemiologic Measurements |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
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