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Synovial biopsies are now routinely performed both in research and in clinical practice. The developments of ultrasound (US) and of US-guided needle biopsies devices have facilitated their use and tolerance by the patients. However, their interest in clinical practice in the context of an undifferentiated arthritis remains debated.
In this study, the investigators will collect all the synovial biopsies performed in clinical practice in 18 Rheumatology Unit throughout France. All the participants received a standardized training on US-guided synovial biopsies. For each biopsy, the indications, clinical presentation, procedure (length, tolerance), biopsy results (Pathology, bacteriology, etc ...) will be collected in a Clinical Research Form. The investigator will determine the number of cases where the synovial biopsy allows drawing a definite diagnosis.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| US-guided synovial biopsy | Other | Needle Synovial biopsy performed using a Tru-cut® device. |
| Measure | Description | Time Frame |
|---|---|---|
| number of cases where the synovial biopsy allows drawing a definite diagnosis | Final diagnosis will be classified in 5 groups: infectious, crystal induced arthritis, tumoral, inflammatory rheumatisms, others (amyloidosis etc …) | 10 days |
| Measure | Description | Time Frame |
|---|---|---|
| Indications, tolerance, complications, number and type of analysis for each sample, results of pathology, bacteriology, mycobacteriology | For each biopsy, the indications, clinical presentation, procedure (length, tolerance), biopsy results (Pathology, bacteriology, etc ...) will be collected in a Clinical Research Form. | 1 month |
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Inclusion Criteria:
All patients undergoing an US-guided synovial biopsy in clinical practice in the context of an arthritis of unknown origin
Exclusion Criteria:
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Age under 18 year old, pregnancy, breastfeeding
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| Name | Affiliation | Role |
|---|---|---|
| Benoit Le Goff | Nantes University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| AP-HP | Paris | Lariboisière | 75475 | France | ||
| AP-HP |
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| ID | Term |
|---|---|
| D001168 | Arthritis |
| ID | Term |
|---|---|
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| Paris |
| Saint-Antoine |
| 75012 |
| France |
| AP-HP | Paris | Salpétrière | 75013 | France |
| Chu d'Angers | Angers | 49000 | France |
| CHU de Bordeaux | Bordeaux | 33000 | France |
| Chu Brest | Brest | 29000 | France |
| CHU CAEN | Caen | 14000 | France |
| Chu de Dijon | Dijon | 21000 | France |
| CHD La Roche-sur-Yon | La Roche-sur-Yon | 85000 | France |
| AP-HM | Marseille | 13000 | France |
| Chu de Montpellier | Montpellier | 34000 | France |
| CHU de Nancy | Nancy | 54000 | France |
| CHU de Nice | Nice | 06000 | France |
| CHU de Poitiers | Poitiers | 86000 | France |
| Chu de Rennes | Rennes | 35000 | France |
| Chu de Strasbourg | Strasbourg | 67000 | France |
| Chu de Toulouse | Toulouse | 31000 | France |