Assessment of Change in AtheROSclerotic Plaque by Serial CCTA (ACROSS) is designed as a prospective observational study which aim is to demonstrate the effect of statins on coronary atherosclerosis, assessed by quantitative analysis of CCTA.

Inclusion Criteria:

• Patients who underwent clinically indicated CCTA (index CCTA)
• Mild to moderate stenosis (25-69%) on CCTA
• ≥1 clinical risk factors (Smoking, HTN, HDL<40, Premature FHx, M ≥45, F ≥55) for CAD

Exclusion Criteria:

• Acute coronary syndrome (unstable angina or MI)
• Positive (not equivocal) stress test
• Contraindications to statin

Patients who underwent clinically indicated CCTA and confirmed to have coronary atherosclerosis will be enrolled.