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| Name | Class |
|---|---|
| Charles University, Czech Republic | OTHER |
| Ministry of Defence and Armed Forces of the Czech Republic | UNKNOWN |
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The aim of the study is to investigate respiratory parameters of a person in the simulated avalanche snow and consequent use of the measured data for development of a mathematical-physical model of breathing during increasing hypercapnia in the avalanche.
The study is a part of a university research project aimed at studying physiological conditions and development of breathing parameters of a person breathing in the simulated avalanche snow. Presence of an air pocket and its size play an important role in survival of victims buried in the avalanche snow. Even small air pockets facilitate breathing, yet they do not provide a significant amount of fresh air for breathing. The investigators hypothesize that the size of the air pocket significantly affects the airflow resistance and work of breathing. The aim of the study is to investigate the effect of the air pocket volume on gas exchange and work of breathing in subjects breathing into the simulated avalanche snow.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Wet snow/Small air pocket | Experimental | Breathing in the simulated avalanche snow. Breathing into model of wet avalanche snow with a small air pocket |
|
| Dry snow/Small air pocket | Experimental | Breathing in the simulated avalanche snow. Breathing into model of dry avalanche snow with a small air pocket |
|
| Wet snow/Large air pocket | Experimental | Breathing in the simulated avalanche snow. Breathing into model of wet avalanche snow with a large air pocket |
|
| Dry snow/Large air pocket | Experimental | Breathing in the simulated avalanche snow. Breathing into model of dry avalanche snow with a large air pocket |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Breathing in the simulated avalanche snow | Other | Breathing in the simulated wet or dry avalanche snow with a small or large air pocket |
|
| Measure | Description | Time Frame |
|---|---|---|
| The length of breathing | Time to termination of the breathing experiment due to the decision of the tested subject, or determined by high end-tidal carbon dioxide value or by the order by the clinician assessing the health status of the subjects. | Continuously within 30 minute interval from the beginning of the breathing experiment |
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| Name | Affiliation | Role |
|---|---|---|
| Karel Roubik, PhD | Czech Technical University in Prague, FBMI | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Czech Technical University, Faculty of Biomedical Engineering | Kladno | 272 01 | Czechia | |||
| Charles University, Czech Republic |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 12867313 | Background | Brugger H, Sumann G, Meister R, Adler-Kastner L, Mair P, Gunga HC, Schobersberger W, Falk M. Hypoxia and hypercapnia during respiration into an artificial air pocket in snow: implications for avalanche survival. Resuscitation. 2003 Jul;58(1):81-8. doi: 10.1016/s0300-9572(03)00113-8. | |
| 17325506 | Background | Bellani G, Patroniti N, Weismann D, Galbiati L, Curto F, Foti G, Pesenti A. Measurement of pressure-time product during spontaneous assisted breathing by rapid interrupter technique. Anesthesiology. 2007 Mar;106(3):484-90. doi: 10.1097/00000542-200703000-00012. |
| Label | URL |
|---|---|
| Work of Breathing into Snow in the Presence versus Absence of an Artificial Air Pocket Affects Hypoxia and Hypercapnia of a Victim Covered with Avalanche Snow: A Randomized Double Blind Crossover Study | View source |
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| ID | Term |
|---|---|
| D006935 | Hypercapnia |
| ID | Term |
|---|---|
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D012119 | Respiration |
| ID | Term |
|---|---|
| D012143 | Respiratory Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |
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| Prague |
| 162 00 |
| Czechia |
| 10807386 | Background | Grissom CK, Radwin MI, Harmston CH, Hirshberg EL, Crowley TJ. Respiration during snow burial using an artificial air pocket. JAMA. 2000 May 3;283(17):2266-71. doi: 10.1001/jama.283.17.2266. |
| 26666523 | Background | Roubik K, Sieger L, Sykora K. Work of Breathing into Snow in the Presence versus Absence of an Artificial Air Pocket Affects Hypoxia and Hypercapnia of a Victim Covered with Avalanche Snow: A Randomized Double Blind Crossover Study. PLoS One. 2015 Dec 14;10(12):e0144332. doi: 10.1371/journal.pone.0144332. eCollection 2015. |
| 29247235 | Background | Strapazzon G, Paal P, Schweizer J, Falk M, Reuter B, Schenk K, Gatterer H, Grasegger K, Dal Cappello T, Malacrida S, Riess L, Brugger H. Effects of snow properties on humans breathing into an artificial air pocket - an experimental field study. Sci Rep. 2017 Dec 15;7(1):17675. doi: 10.1038/s41598-017-17960-4. |
| 35136116 | Derived | Roubik K, Sykora K, Sieger L, Ort V, Horakova L, Walzel S. Perlite is a suitable model material for experiments investigating breathing in high density snow. Sci Rep. 2022 Feb 8;12(1):2070. doi: 10.1038/s41598-022-06015-y. |