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C2-C4 compartment block compared to the Costaiola block, in the control of persistent postoperative pain (somatic and neuropathic) in patients undergoing carotid thromboendarterectomy
A comparative analysis will assess the somatic pain (scores ≥4 on the NRS scale) and neurapathic pain (by the Lindblom roller and Von Frei hair tests) between group A (block group of the C2-C4 compartment ) and the control group B (block group according to Costagliola), during the 3 months after surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| C2-C4 compartment block | Experimental | Experimental: the C2-C4 compartment anesthetic block is performed by injecting Levobupivacaine 0.375% 20 mL between the posterior face of the middle scalenous muscle, the anterior face of the posterior scalene muscle and the lower plane of the sternoscleidomastoid muscle. |
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| Costagliola block | Active Comparator | Active Comparator: the Costagliola anesthetic block is performed by injecting Levobupivacaine 0.375% 20 mL injected in the posterior margin of the sternocleidomastoid muscle and along the anterior border of the same muscle. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| C2-C4 compartment anesthetic block | Procedure | C2-C4 compartment anesthetic block is performed by injecting levobupivacaine 0.375% 20 mL between the posterior face of the middle scalenus muscle, the anterior face of the posterior scalene muscle and the lower plane of the sternoscleidomastoid muscle. |
| Measure | Description | Time Frame |
|---|---|---|
| somatic pain | Somatic pain assessed by Numeric Pain Rating Scale for pain (the 11-point numeric scale ranges from '0' representing "no pain" to '10' representing the "worst pain imaginable" | 3 mounths after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Opiates request | Request of opiates, assessed in mg of equianalgesic dose of morphine after 3 mouths from surgery | 3 mounths after surgery |
| Pregabalin request | Pregabalin request in mg, 3 months after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Emiliano Petrucci, MD | SS Filippo and Nicola Academic Hospital of Avezzano | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| SS Filippo and Nicola Academic Hospital of Avezzano | Avezzano | L'Aquila | 67051 | Italy |
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| ID | Term |
|---|---|
| D059226 | Nociceptive Pain |
| D009437 | Neuralgia |
| ID | Term |
|---|---|
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Costagliola block | Procedure | Costagliola block is performed by injected by injecting levobupivacaine 0.375% 20 mL along the anterior and the posterior border of sternocleidomastoid muscle |
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| 3 months |
| Neuropathic pain | Presence of neuropathic disturbances, assessed with von Frey hair test and Lindblom test | 3 months |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |