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To evaluate the efficacy and safety of internal fixation or arthroplasty for hip fracture patients over 75 years of age with multiple medical complications through the operation time, intraoperative bleeding, time to start weight bearing activities and other indicators.
Patients will be enrolled from five study centers, each center will be free with regard to surgical indications and postoperative prescription. The unstable fractures were A2 and A3 (31 A2.2 and 3, and 31 A3.3) according to the AO classification. The investigators will use a prospective randomized approach to determine the treatment procedure for patients. The patients undergoing arthroplasty will be regarded as the experimental group and the patients who accept the intramedullary nail fixation will be regarded as the positive control group. All patients will receive consistent anticoagulant, analgesic and other therapeutic measures in the perioperative period except for the different surgical methods. The two groups will be compared in age, sex, pre-fracture place of residence, fracture type and preoperative comorbidity. The investigators will evaluate the effect and safety of the two types of operations by comparing the surgical related data, complication incidence and functional rehabilitation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Joint replacement | Experimental | Intertrochanteric fracture patients were treated with joint replacement surgery.The postoperative drainage volume, blood transfusion volume, intraoperative blood loss, operative time, early weight bearing time will be recorded, and postoperative pulmonary infection, urinary tract infection, bedsore incidence and postoperative functional rehabilitation will be observed. |
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| Intramedullary nail fixation | Active Comparator | Intertrochanteric fracture patients were treated with intramedullary nail fixation surgery.The postoperative drainage volume, blood transfusion volume, intraoperative blood loss, operative time, early weight bearing time will be recorded, and postoperative pulmonary infection, urinary tract infection, bedsore incidence and postoperative functional rehabilitation will be observed. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Joint replacement surgery | Procedure | Joint replacement surgery is to replace the original joint function, so that the patient can recover the joint function as soon as possible. |
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| Measure | Description | Time Frame |
|---|---|---|
| Bleeding related index | Postoperative drainage volume and bleeding volume during operation(Unit: ml) | Three days after the operation |
| Measure | Description | Time Frame |
|---|---|---|
| Joint rehabilitation index | Early loading time | Three months after the operation |
| Complication rate | The incidence of postoperative lung infection, urinary tract infection, bedsore and mortality |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Baoguo Jiang, Doctor | Peking University People's Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking University People's Hospital | Beijing | 100044 | China |
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| ID | Term |
|---|---|
| D006620 | Hip Fractures |
| ID | Term |
|---|---|
| D005264 | Femoral Fractures |
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
| D025981 | Hip Injuries |
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| ID | Term |
|---|---|
| D001178 | Arthroplasty |
| ID | Term |
|---|---|
| D019637 | Orthopedic Procedures |
| D013514 | Surgical Procedures, Operative |
| D019651 | Plastic Surgery Procedures |
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| Intramedullary nail fixation | Procedure | Internal fixation surgery is the stable fixation of fracture, which provides the condition for the restoration of joint function. |
|
| Three monthes after the operation |
| Functional rehabilitation index | Harris Scores of the two groups | Three months after the operation |
| Surgical related index | operation time of the two groups(Unit: minutes) | Three days after the operation |
| D007869 |
| Leg Injuries |