Kidney Function in Diabetics During CPB (Cardio Pulmonary Bypass)

The Effect of the CPB on Kidney Blood Flow, Function and Oxygen Uptake During Open Heart Surgery in Patients With Diabetes Mellitus

Filtration of urine in the kidney requires sufficient oxygen supply. The filtration of urine is greater in patents with diabetes. Our theory is that the diabetic kidney has a higher oxygen demand than the non diabetic kidney thereby making the diabetic kidney more sensitive to decreased oxygen delivery following reduced blood flow. With a catheter inserted into the kidney vein we will monitor the blood flow and oxygen saturation before and during CPB, in patient with diabetes.

Inclusion Criteria:

• Patients with diabetes mellitus
• Serum creatinine < 150 micromol/L preoperative
• Heart surgery requiring CPB
• LV (left ventricle) EF >40 %
• Normal hemoglobin

Exclusion Criteria:

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