Subcutaneous Suppressive Antibiotic Therapy for Bone and Joint Infections

Subcutaneous Suppressive Antibiotic Therapy for Bone and Joint Infections

For patients having a bone or joint infections, with or without device, optimal surgical therapy could be sometimes non-feasible, especially in the elderly population. Therefore, a medical therapy with oral prolonged suppressive antibiotic therapy (PSAT) seems to be an option to prevent recurrence and prosthesis loosening.

Subcutaneous (SC) administration of injectable intravenous antibiotics as prolonged suppressive antibiotic therapy could be a convenient way when oral treatment is not available to facilitate ambulatory care, this practice being considered as routine care.

The aim of this study is to evaluate tolerance and efficacy of subcutaneous administration of antibiotics for prolonged suppressive antibiotic therapy in patients having this treatment as part of their routine care.

Inclusion Criteria:

• patients having bone or joint infection,
• patients with or without device treated by sub-cutaneous prolonged antibiotic therapy

Exclusion Criteria:

• diabetic foot osteomyelitis
• pressure ulcer-associated osteomyelitis