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clinical comparison between alvogyl and gelatin sponge when used to protect the denuded area of the palatal donor site after free gingival graft in means of reducing pain and healing.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control group | Active Comparator | Gelatin Sponge Sheet is a heamostatic agent act as a mechanical barrier to protect the palatal donor site |
|
| intervention group | Experimental | alvogyl in a paste form with analgesic action to protect the palatal donor site and help to relief pain |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gelatin Sponge Sheet | Drug | sheets act as a mechanical barrier used to protect the denuded area of the palatal donor site |
|
| Measure | Description | Time Frame |
|---|---|---|
| pain score | recorded by the pain trough a Visual Analogue scale score (between 0 and 10. 0: no pain, 1: minimal pain,10: severe pain) | 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| healing | healing of the palatal mucosa using H2O2 Test this test is based on the principle that if the epithelium is discontinuous, then H2O2 diffuses into the CT, the enzyme catalase acts on H2O2to release water and oxygen. This is shown clinically by the production of bubbles on the wound. The area to be evaluated is then dried, and 3% H2O2 is sprinkled on the wound with a syringe, waiting for the appearance of bubbles, which will suggest that the surgical site is not completely epithelialized. Complete healing will be recorded as a dichotomous variable (yes/no). |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32144515 | Derived | Ehab K, Abouldahab O, Hassan A, Fawzy El-Sayed KM. Alvogyl and absorbable gelatin sponge as palatal wound dressings following epithelialized free gingival graft harvest: a randomized clinical trial. Clin Oral Investig. 2020 Apr;24(4):1517-1525. doi: 10.1007/s00784-020-03254-z. Epub 2020 Mar 6. |
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| ID | Term |
|---|---|
| D000073818 | Pain, Procedural |
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D014622 | Vaginal Creams, Foams, and Jellies |
| C013804 | butyl aminobenzoate, eugenol, iodoform, spearmint oil drug combinations |
| ID | Term |
|---|---|
| D004304 | Dosage Forms |
| D004364 | Pharmaceutical Preparations |
| D053566 | Feminine Hygiene Products |
| D004864 | Equipment and Supplies |
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| Alvogyl | Drug | paste form with analgesic action to protect the palatal donor site and help to relief pain |
|
|
| 4 weeks |
| bleeding | Questionaire, Binary (yes or no). | 2 weeks |
| analgesic consumption | questionaure, Numerical, Amount of analgesics daily consumption | 2 weeks |