Clinical Impact of Dedicated MR Staging of Ovarian Cancer

Clinical Impact of Dedicated MR Staging of Ovarian Cancer

The only chance of cure for patients with advanced stage ovarian cancer is complete cytoreductive surgery (CRS). The only way to determine whether complete CRS can be achieved is by a laparoscopy. However, diffusion-weighted magnetic resonance imaging (DW-MRI) has a very high sensitivity to detect small volume malignant disease, making it a potentially suitable staging tool. Aim of this study is to determine the performance of DW-MRI for predicting whether complete CRS can be achieved.

Inclusion Criteria:

• Patients with advanced stage (FIGO stage III or IV) ovarian cancer scheduled for primary or interval cytoreductive surgery
• Age >18 years
• Written and signed informed consent
• WHO 0-2
• Able to read and write Dutch

Exclusion Criteria:

• Patients with contraindications for MRI
• Patients with contraindications for CRS
• Known additional malignancy