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Probiotics, which are part of the human body, are microorganisms, which are known to have beneficial effects when consumed in a certain amount, and have the function of controlling intestinal flora and inhibiting inflammation. Recently, probiotics have received much attention in the treatment of hypersensitivity syndrome. The aim of this study was to investigate the effect of probiotic strains, ID-JPL934, in the diagnosis of irritable bowel syndrome.
Overall satisfaction with improvement of bowel habits such as diarrhea and constipation as well as abdominal discomfort and abdominal discomfort in the group receiving ID-JPL934 capsules (test food group or test group) and control group (control food group or control group) (0-10 point visual analogue scale) for each symptom before and after ingestion to evaluate the degree of improvement of the symptoms. The purpose of this study was to investigate the relationship between bacterial composition changes in the stool and the improvement of symptoms in the patients before and after ingestion.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ID-JPL934 | Experimental | probiotics 20%, corn starch 80% |
|
| placebo | Placebo Comparator | corn starch 100% |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ID-JPL934 | Dietary Supplement | probiotics |
| |
| Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| symptom improvement effect | symptom questionnaire survey | 8week |
| Measure | Description | Time Frame |
|---|---|---|
| VAS score | Visual analogue scale score(10-point scales) | 8week |
| QoL score | Quality of Life score (5-point scales) | 8week |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Bungdang Hospital | Seongnam-si | Gyeonggi-do | 13620 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34158518 | Derived | Shin CM, Choi YJ, Lee DH, Moon JS, Kim TY, Kim YK, Lee WH, Yoon H, Park YS, Kim N. Validity and safety of ID-JPL934 in lower gastrointestinal symptom improvement. Sci Rep. 2021 Jun 22;11(1):13046. doi: 10.1038/s41598-021-92007-3. |
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| ID | Term |
|---|---|
| D003967 | Diarrhea |
| D015746 | Abdominal Pain |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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randomized, double-blind, placebo-controlled, parallel-group
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| Dietary Supplement |
corn starch |
|
| D009461 | Neurologic Manifestations |