The NOrdic-Baltic Randomized Registry Study for Evaluation of PCI in Chronic Total Coronary Occlusion

The NOrdic-Baltic Randomized Registry Study for Long-term Clinical Evaluation of Adjunction of PCI to Optimal Medical Therapy in Chronic Total Coronary Occlusion

Randomized registry for the study of CTO PCI as adjunction to optimal medical therapy.

Inclusion Criteria:

• ≥1 CTO lesion amenable to PCI.
• Stable and stabilized coronary artery disease
• Symptoms (angina pectoris or shortness of breath) and/or signs of reversible perfusion defect by SPECT, PET or MR and/or angiographic/echocardiographic indication of reversible ischemia.
• CTO lesion in a major coronary vessel supplying a significant myocardial territory (vessel diameter usually ≥3mm).

Exclusion Criteria:

• Expected survival <1 year.
• Renal failure on dialysis.
• Stable non-CTO lesions treated within one month.
• Declined informed consent.
• Regarding CMR: allergy to contrast medium, severe obesity, claustrophobia and certain metallic implants