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Investigators assess and compare postoperative sore throat and hoarseness in the group maintaining moderate relaxation and deep relaxation during operation.
In this sturdy, the deep block is applied when the surgeon requests for deep muscle relaxation to improve surgical field condition in the surgery such as laparotomy known that the deep block is helpful and in the other surgeries, the moderate block is maintained. The investigators assess the postoperative sore throat and hoarseness and compare the effect of muscle relaxation depth in the deep block group and moderate block group in terms of the incidence and severity of postoperative sore throat and hoarseness.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Moderate muscle relaxation | Active Comparator | Rocuronium is administered to maintain moderate relaxation during operation. This is conventional muscle relaxation level of this institute. |
|
| Deep muscle relaxation | Experimental | Rocuronium is administered to maintain deep relaxation during operation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Rocuronium(deep) | Drug | In the group with deep relaxation during surgery, rocuronium is given by continuous infusion (0.6 mg/kg/h). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Overall incidence of postoperative sore throat | The overall cumulative incidence of postoperative sore throat is assessed in the 24-hr evaluation period | Within 24 hrs after operation |
| Measure | Description | Time Frame |
|---|---|---|
| The incidence of postoperative sore throat | The presence of sore throat is assessed. | At 1,6, and 24 hrs after operation |
| The severity of postoperative sore throat | The severity of sore throat is assessed by using a 100-point numerical ratig scale (NRS, 0 [no pain], 100 [worst pain imaginable]). |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jee-Eun Chang, M.D | Contact | 82-2-870-2517 | sw411528@hanmail.net |
| Name | Affiliation | Role |
|---|---|---|
| Jee-eun Chang, M.D | SMG-SNU Boramae Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Jee-Eun Chang | Recruiting | Seoul | 07061 | South Korea |
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| ID | Term |
|---|---|
| D010612 | Pharyngitis |
| D009123 | Muscle Hypotonia |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D010608 | Pharyngeal Diseases |
| D009057 | Stomatognathic Diseases |
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| Rocuronium(moderate) | Drug | In the group with deep relaxation during surgery, rocuronium is given by bolus dose(0.15mg/kg) induced a train of four count of 1-2. |
|
| At 1,6, and 24 hrs after operation |
| Incidence and severity of postoperative hoarseness | Hoarseness is defined as a voice quality different from the preoperative voice and graded as follows: none (no hoarseness), mild (recognized by the patient), moderate (obvious to the investigator), and severe (aphonia). | At 1,6, and 24 hrs after operation |
| Postoperative analgesic consumption | The amount of patient-controlled analgesia and other analgesic medication used | Within 24 hrs after operation |
| D012140 |
| Respiratory Tract Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |