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| ID | Type | Description | Link |
|---|---|---|---|
| 2017-A01847-46 | Registry Identifier | ANSM Register |
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The identification of a high atropine load of treatment received during hospitalization as a predictor of postoperative confusion could have various benefits:
In total, the present study would improve the daily management of hospitalized patients and the practices of clinicians, by offering a decision-making aid.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Aged patients | Data collection of patients admitted to the orthopedic department of the University Hospital of Toulouse for surgical management of a fracture of the upper end of the femur in emergency or for the installation of a hip or knee prosthesis. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Data collection | Other | The collection of data will be done by interrogation of the patient and his family / entourage and rereading of medical records |
|
| Measure | Description | Time Frame |
|---|---|---|
| Association between atropine load of medications on the risk of postoperative confusion | Occurrence of a postoperative confusion syndrome performed by Confusion Assessment Method (CAM) scale once a day. The CAM is a validated scale as a diagnostic scale for confusional syndrome at the patient's bedside with four parts : 1) confusion and fluctuation of symptoms, 2) inattention, 3) disorganization of thought, 4) disorder of consciousness. | up to 7 days |
| Atropinic load of drugs | The DURAN scale is the most recent and most comprehensive atropine load evaluation scale. This scale classifies the evaluated drugs into three categories: no anticholinergic power (atropine weight = 0), low anticholinergic activity (atropine weight = 1), high atropinic power (atropine weight = 3). All drugs received by the patient during 7 days will be classified with the Duran scale. | up to 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Duration of hospitalization | Number of days of hospitalization (days) between surgery and discharge. Association between atropinic load of drugs and duration of hospitalization will be evaluated. | Up to discharge, an average of ten days |
| Autonomy |
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Inclusion Criteria:
Exclusion Criteria:
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The recruitment of patients will be ensured from the consultation of anesthesia or the entry into hospitalization by the anesthesia team of the orthopedic surgery department of the Hospital.
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| Name | Affiliation | Role |
|---|---|---|
| Vincent Minville | University Hospital, Toulouse | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pierre-Paul-Riquet University Hospital | Toulouse | 31000 | France |
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| ID | Term |
|---|---|
| D003221 | Confusion |
| ID | Term |
|---|---|
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D003625 | Data Collection |
| ID | Term |
|---|---|
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
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Description of autonomy of the patient at three months of surgery evaluated by the Activity Daily Living scale (ADL). The ADL scale evaluates activities of daily living: washing, dressing, going to the bathroom, ensuring transfers, continence and food. Each item is rated according to a level of dependence: independent (1 point), with assistance (0.5 points), unable to achieve (0 points). A total of 6 points indicates a total autonomy, and 0 a total dependency.
| Month 3 |
| Cognitive dysfunction | Appearance postoperative cognitive dysfunction by the Mini Mental State (MMS). the total score of MMS wil be collected. | baseline |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |