Hyperglycemic Response and Steroid Administration After Surgery (DexGlySurgery)

Hyperglycemic Response to Steroid Administration After Noncardiac Surgery in Patients With and Without Diabetes

The hyperglycemic response to surgery and the added effect of low-dose steroids (dexamethasone 4 to 8mg), and whether these differ in diabetics and nondiabetics remain unclear. Therefore, we prospectively evaluate the intraoperative and postoperative serum glucose concentrations in diabetics and nondiabetics that received intravenous steroid administration. This multicentre study include > 250 patients.Primary endpoiunt was glucose concentration at H6 after surgery. Secondary endpoints were glucose concentration at H12 and at H24 and effect of anesthesia (regional anesthesia)

Inclusion Criteria:

• elective surgery under anesthesia

Exclusion Criteria:

• < 50 kg
• emergency
• insulin therapy
• cardiac surgery
• refusal
• hyperglycemia> 2g/L