Trial of Unicompartmental Versus Total Knee Arthroplasty

A Prospective Randomized Trial of Unicompartmental Versus Total Knee Arthroplasty for the Treatment of Medial Compartment Osteoarthritis

This study is a prospective, randomized trial to compare patient outcomes of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) for the treatment of medial compartment osteoarthritis.

Inclusion Criteria:

• medial compartment osteoarthritis of the knee
• knee flexion greater than greater than 90 degrees
• flexion contracture of less than 10 degrees
• varus deformity < 20 degrees
• grade IV degeneration of the medial compartment

Exclusion Criteria:

• lateral compartment degenerative changes
• previous lateral meniscectomy
• anterior cruciate ligament deficiency
• body mass index > 40
• inflammatory arthritis
• history of septic arthritis
• hemoglobin A1c > 8.0
• chronic liver disease
• stage 3A or greater chronic renal disease
• active IV drug abuse
• patients requiring thromboembolic prophylaxis