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| Name | Class |
|---|---|
| SCARF (Schizophrenia Research Foundation ,India) Schizophrenia | UNKNOWN |
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The aim of this study is to examine whether yoga is efficacious as an add-on treatment for negative symptoms of schizophrenia in a randomized multi-centric trial and also to examine functional brain changes associated with self-reflection after treatment with yoga.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Yoga arm | Active Comparator | Patients with Schizophrenia will undergo 12 sessions of yoga. According to randomization one group of patients will start yoga immediately after recruitment ,whereas another group will go into wait list for 12 weeks after which they will also undergo Yoga treatment. |
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| Control arm | No Intervention | Healthy volunteers who will not receive yoga. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Yoga arm | Behavioral | Yoga module developed for patients with Schizophrenia |
|
| Measure | Description | Time Frame |
|---|---|---|
| Improvement in negative symptoms in patients with schizophrenia | Schizophrenia patients receiving yoga as add-on treatment will have significant improvement in negative symptoms after yoga therapy compared to those in the wait-list group as reflected by a greater decrease in Scale for Assessment of negative symptoms score. This scale measures negative symptoms on a 25 item, 6-point scale. Items are listed under the five domains of affective blunting, alogia, avolition/apathy, anhedonia/asociality, and attention. A higher score indicates greater severity. | At the end of 12 weeks of yoga |
| Measure | Description | Time Frame |
|---|---|---|
| fMRI changes | Schizophrenia patients receiving yoga will have higher activation in Medial prefrontal cortex after yoga therapy compared to baseline and compared to those in the wait-list group at 12 weeks. | At the end of 12weeks |
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Inclusion Criteria:
Schizophrenia Subject
Healthy volunteers:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Naren P Rao, MD | National Institute of Mental Health and Neuro Sciences, India | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Institute of Mental Health and Neurosciences | Bangalore | Karnataka | 560029 | India |
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| ID | Term |
|---|---|
| D012559 | Schizophrenia |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D001523 | Mental Disorders |
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