Investigators want to use 18F-FDG PET/CT imaging to reflect tumor perfusion and hypoxia.

Perfusion and hypoxia were independent prognositic parameters for tumor patients. Developing a method that can evaluate tumor perfusion and hypoxia noninvasively and conveniently was in urgent need. 18F-FDG PET/CT imaging could reflect tumor hypoxia in 60min balanced imaging was proved and accepted. Moreover, FDG could diffuse out of the vasculature and through cell membranes passively and rapidly due to its lipophilicity, its regional uptake at initial times is expected to reflect tumor perfusion. So, investigators want to use 18F-FDG PET/CT imaging to evaluate tumor perfusion and hypoxia simutaniously，in order to guide the clinical diagnosis and treatment.

Inclusion Criteria:

• 1.solid tumor proved by pathology(d>3.0cm);
• 2.age>18-year-old;
• 3. Karnofsky performance status >70;
• 4.sign the informed consent.

Exclusion Criteria:

• 1.There are obvious metal implants near the tumor;
• 2.Can not lie still for 15 minutes.
• 3.Pregnancy.

Tumor patients aged more than 18 years with a histological confirmed diagnosis were eligible in our research. And all patients signed a written informed consent.