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Involutional ptosis is a known eyelid pathology in which the eyelid margin obscures part of the visual axis (MRD1).Patients usually complains of visual field disturbance, deterioration in quality of life and a poor cosmetic appearance.
In clinical practice, two main surgical approaches are performed to the repair of involutional ptosis:
in this prospective study, patients with involutional ptosis will be randomized to each of surgical approaches groups, parameters concerning surgical and post surgical periods will be evaluated.
Involutional ptosis is a known eyelid pathology in which the eyelid margin obscures part of the visual axis (MRD1).Patients usually complains of visual field disturbance, deterioration in quality of life and a poor cosmetic appearance.
In clinical practice, two main surgical approaches are performed to the repair of involutional ptosis:
in this prospective study, patients with involutional ptosis will be randomized to each of surgical approaches groups, parameters concerning surgical and post surgical periods will be evaluated.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| anterior approach | Active Comparator | patients having involutional ptosis undergoing anterior approach surgical ptosis repair (Levator advancement) |
|
| posterior approach | Active Comparator | patients having involutional ptosis undergoing posterior approach surgical ptosis repair (mullerectomy) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Blepharoptosis repair | Procedure | levator advancement or mullerectomy |
|
| Measure | Description | Time Frame |
|---|---|---|
| MRD1 | Distance in millimeters between corneal light reflex and upper eyelid margin | 6 months |
| surgery duration | Time from first incision to last suture (in minutes) | 3 hours |
| Levator function | change (in millimeters) in upper eyelid position from downgaze to maximal upgaze | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Need for additional eyelid surgery | Any need for oculoplastic additional surgical interventions (Descriptive) | 6 months |
| Eyelid or ocular secondary disease | Descriptive |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Arie Nemet, Prof. (MD) | Contact | +972-9-7471527 | nemet.arik@gmail.com | |
| Tal Sharon, Dr.(MD) | Contact | +972-7472154 | +972-544831188 | tal.sharon.p@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Arie Nemet, Prof. (MD) | ophthalmology depertmant, MeirMc, Israel | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27429227 | Background | Patel RM, Aakalu VK, Setabutr P, Putterman AM. Efficacy of Muller's Muscle and Conjunctiva Resection With or Without Tarsectomy for the Treatment of Severe Involutional Blepharoptosis. Ophthalmic Plast Reconstr Surg. 2017 Jul/Aug;33(4):273-278. doi: 10.1097/IOP.0000000000000748. | |
| 22186506 | Background | Chang S, Lehrman C, Itani K, Rohrich RJ. A systematic review of comparison of upper eyelid involutional ptosis repair techniques: efficacy and complication rates. Plast Reconstr Surg. 2012 Jan;129(1):149-157. doi: 10.1097/PRS.0b013e318230a1c7. |
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| 6 months |
| 25719375 | Background | Sohrab MA, Lissner GS. Comparison of Fasanella-Servat and Small-Incision Techniques for Involutional Ptosis Repair. Ophthalmic Plast Reconstr Surg. 2016 Mar-Apr;32(2):98-101. doi: 10.1097/IOP.0000000000000417. |
| 15953636 | Background | Ben Simon GJ, Joseph J, Lee S, Schwarcz RM, McCann JD, Goldberg RA. External versus endoscopic dacryocystorhinostomy for acquired nasolacrimal duct obstruction in a tertiary referral center. Ophthalmology. 2005 Aug;112(8):1463-8. doi: 10.1016/j.ophtha.2005.03.015. |
| 8437835 | Background | Liu D. Ptosis repair by single suture aponeurotic tuck. Surgical technique and long-term results. Ophthalmology. 1993 Feb;100(2):251-9. doi: 10.1016/s0161-6420(93)31662-3. |