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The aim of our study is to assess the value of administration of prostaglandins before cesarean section to reduce the amount of blood loss
160 full term pregnant patients candidate for elective cesarean section were randomly allocated into 2 groups ,80 patients will receive 200mcg of rectal prostaglandins before cesarean section and 80 patients are used as control receiving placebo
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A (Misoprostol group) | Active Comparator | 200 mcg rectal Misoprostol administration before cesarean section |
|
| Group B (control group) | Placebo Comparator | No prostaglandins administration before cesarean section |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Misoprostol 200Mcg Tab | Drug | administration of 200 Mcg of misoprotol rectal |
| |
| Measure | Description | Time Frame |
|---|---|---|
| amount of intraoperative blood loss | number of soaked towels | during cesarean section |
| postpartum hemorrhage | blood loss after cesarean section | 24 hour after cesarean section |
| Measure | Description | Time Frame |
|---|---|---|
| fetal condition | apgar score | 5 minutes after cesarean section |
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Inclusion Criteria:pregnant patients full term elective cesarean section
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Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kasr El Ainiy Hospital | Cairo | 11562 | Egypt |
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| ID | Term |
|---|---|
| D016595 | Misoprostol |
| ID | Term |
|---|---|
| D011459 | Prostaglandins E, Synthetic |
| D011465 | Prostaglandins, Synthetic |
| D011453 | Prostaglandins |
| D015777 | Eicosanoids |
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| elective cesarean section |
| Procedure |
elective cesarean section for full term patients |
|
| D005231 |
| Fatty Acids, Unsaturated |
| D005227 | Fatty Acids |
| D008055 | Lipids |
| D012898 | Autacoids |
| D018836 | Inflammation Mediators |
| D001685 | Biological Factors |