Progesterone Variation on the Final Day of Oocyte Maturation.

Progesterone Variation on the Final Day of Oocyte Maturation. A Prospective Cohort Study With Repeated Measurements

The current study, aims through a robust design to provide a simple answer on whether progesterone levels of the same individual may significantly vary depending on the time of blood retrieval before the ovulation triggering, by evaluating the daily variability of serum progesterone on the day of triggering in healthy women who perform a COS for oocyte donation, through multiple blood samplings.

Inclusion Criteria:

• Healthy oocyte donors according to spanish law for oocyte donation
• Controlled ovarian stimulation following a flexible antagonist protocol and stimulation with recombinant Follicular stimulating hormone.
• Informed consent signed

Exclusion Criteria:

• Detection of luteinizing hormone surge before triggering