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Levels of blood pressure in adolescents with preeclampsia and eclampsia:
Multicenter case-control study (Latin America). Maternities in Latin America: Two hospitals in Panama, one hospital in Mexico, one hospital in El Salvador, one hospital in Guatemala, two hospitals in Honduras, one hospital in Colombia, two hospitals in Peru and two hospitals in Bolivia.
The objective is to evaluate the basal levels of blood pressure during pregnancy and determine if there is any increase that is associated with the development of preeclampsia and eclampsia without reaching the known values of 140/90 mm Hg.
The sample is 1050: (350 Cases and 700 Controls).
Levels of blood pressure in adolescents with preeclampsia and eclampsia: cases and controls study.
It is unknown whether the blood pressure levels used for the diagnosis of preeclampsia have the same impact in adolescents as in older women, however for the diagnosis of preeclampsia and severe hypertension the same criteria of hypertension are used regardless of age maternal.
It is necessary to do research to determine the values of blood pressure with which adolescents convulse and also to validate if slight increases in baseline blood pressure in adolescents are associated with prediction of preeclampsia and eclampsia.
Unfortunately, 85% of teenage pregnancies occur in non-industrialized countries such as those in Latin America, and it is estimated that 25% of maternal deaths occur in adolescents
Cases: patients with pregnancy that starts before the age of 19 that develops preeclampsia (mild), severe preeclampsia, gestational hypertension and eclampsia, that is 24 and more weeks pregnant with prenatal control started before 20 weeks of pregnancy. Controls are patients with the same criteria but WITHOUT hypertension during this pregnancy.
The statistical analyzes are based on comparing blood pressure levels between the two groups, in addition blood pressure levels like 30/15 on the systolic and diastolic basal levels will be created and compared between the two groups, especially when it is not possible to have 140 / 90 mm Hg.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cases | Cases: patients with pregnancy that starts before the age of 19 that develops preeclampsia (mild), severe preeclampsia, gestational hypertension and eclampsia, that is 24 and more weeks pregnant with prenatal control started before 20 weeks of pregnancy. | ||
| controls | Are patients with pregnancy that starts before the age of 19 that without develops (preeclampsia mild), severe preeclampsia, gestational hypertension or eclampsia) that is 24 and more weeks pregnant with prenatal control started before 20 weeks of pregnancy. |
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| Measure | Description | Time Frame |
|---|---|---|
| Levels of blood pressure | Level of blood pressure during pregnancy or delivery | after 24 weeks of gestactión to delivery. |
| Measure | Description | Time Frame |
|---|---|---|
| severe hypertension | hypertension more thet 160 mmHg on systolic or 110 mmHg on diastolyc. | after 24 weeks of gestactión to delivery. |
| parity | number of previous birth |
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Inclusion Criteria:
Exclusion Criteria:
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Pregnant patients who are 19 years of age or younger and more than 23 weeks pregnant, where the cases are those that develop preeclampsia (mild), severe preclampsia, gestational hypertension and eclampsia; and the controls patients of the same age and with more than 23 weeks of pregnancy without hypertension.
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| Name | Affiliation | Role |
|---|---|---|
| Paulino Vigil | Complejo CSS | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital del seguridad social La Paz | La Paz | Bolivia | ||||
| Hospital de Pereira |
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| ID | Term |
|---|---|
| D011225 | Pre-Eclampsia |
| D004461 | Eclampsia |
| ID | Term |
|---|---|
| D046110 | Hypertension, Pregnancy-Induced |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| birth before actual pregancy |
| Pereira |
| Colombia |
| Hospital de IGSS, Guatemala | Guatemala City | Guatemala |
| Hospial de Honduras | Tegucigalpa | Honduras |
| Complejo Hospitalario CSS | Panama City | Panama |
| Santo Tomás | Panama City | Panama |
| Hospital Regional de Cajamarca | Cajamarca | Peru |
| Hospital Nacional Docente Madre Niño, San Bartolomé, | Lima | Peru |