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| Name | Class |
|---|---|
| Shenzhen Sun Yat-sen Cardiovascular Hospital | OTHER |
| Wujin People's Hospital | OTHER |
| Chongqing Zhongshan Hospital | OTHER_GOV |
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To test the changes in osteoarthritis according to the X-rays, and changes in bone quality before and 1 or more years after beginning the jogging
Patients in this research are given an entry Bone Densitometry(DEXA)scan and are required to advance from 3-minute jogging a day to 10-minute level in daily practice for 1 year as instructed. After 1 year, subsequent DEXA scans are recorded. Interested participants are also encouraged to have hip and spine X-rays, and bone quality studies on study entry and two years later. Actual subject participation, intercurrent illnesses, fractures and changes in medication are self-monitored. Results are calculated by change in bone mineral density in the lumbar spine, hips and femurs by the DEXA scan in the study. Dose-response relationships between the amount of jogging and bone mineral density are sought. Jogging-related fractures and other adverse effects are also noted.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| jogging | Experimental | At least 5 times/week |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| jogging | Behavioral | Jogging as instructed for 1 year |
|
| Measure | Description | Time Frame |
|---|---|---|
| DEXA T-score | Bone mineral density change in spine, hip and femur after 1 year of jogging | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Number of fractures | Number of fractures occurring while in study | 1 year |
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Inclusion Criteria:
Past DEXA scan and, all within 6 months of study entry, DEXA scan and normal values for: Metabolic panel, TSH, PTH, ESR (or CRP), Vitamin D 25 hydroxy, Vitamin D 1,25 dihydroxy, Urine NTX
Exclusion Criteria:
Known metabolic bone disease such as osteogenesis imperfecta, current treatment with steroids, chemotherapy, or currently healing fractures of lumbar spine, hips or femurs, severe heart disease
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Peixun Zhang, MD | Contact | 15210802766 | 875274428@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Peixun Zhang, MD | Peking University People's Hospital | Principal Investigator |
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| ID | Term |
|---|---|
| D010024 | Osteoporosis |
| D001847 | Bone Diseases |
| ID | Term |
|---|---|
| D001851 | Bone Diseases, Metabolic |
| D009140 | Musculoskeletal Diseases |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D007590 | Jogging |
| ID | Term |
|---|---|
| D012420 | Running |
| D008124 | Locomotion |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
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| D055687 |
| Musculoskeletal and Neural Physiological Phenomena |
| D015444 | Exercise |
| D009043 | Motor Activity |