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The present study will analyze if exercise is able to elicit the well-known anti-atherogenic effects in patients with SCI. This will be evaluated by measuring vascular parameters such as endothelial and inflammatory blood markers, echocardiography of the heart and peripheral vessels, as well as blood pressure and arterial stiffness, in subjects performing either wheelchair dancing, wheelchair marathon or no sports. Further, it will be investigated, whether there is an association between neuroplasticity and cardiovascular health, as measured by electroencephalography (EEG), transcranial magnetic stimulation (TMS) and blood levels of the brain-derived neurotrophic factor (BDNF).
We hypothesize that the cardiovascular, physical and psychological benefits of wheelchair dancing and/or wheelchair marathon parallel improved neuroplasticity in SCI-patients
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control | healthy walking control participants | ||
| wheelchair dancer | wheelchair users, who are performing wheelchair dancing | ||
| wheelchair marathon participants | wheelchair users, who are participants in wheelchair/ handbike Marathon competitions | ||
| sedentary wheelchair patients | wheelchair users, who conduct exercise bouts less than 2 times per month |
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| Measure | Description | Time Frame |
|---|---|---|
| comparison of cardiovascular risk factors between different study groups | measurement for arterial stiffness parameters, via pulse wave analysis. Comparison between healthy individuals and patients using wheelchairs (three different groups). | October 2017- June 2018 |
| Evaluation of echocardiography results between different study groups | Evaluation of echocardiography comparing healthy individuals and patients using wheelchairs (three different groups). | October 2017- June 2018 |
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Inclusion Criteria:
wheelchair users independent of the cause of the walking impairment, preferably with spinal cord injury.
Exclusion Criteria:
metallic implanters, additional neurologic pathologies, pregnancy
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healthy participants, wheelchair users
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Neurology, Christian Doppler Klinik, Paracelsus Medical University Salzburg | Salzburg | 5020 | Austria | |||
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| ID | Term |
|---|---|
| D013119 | Spinal Cord Injuries |
| ID | Term |
|---|---|
| D013118 | Spinal Cord Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
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| Department of Sports Medicine, Prevention and Rehabilitation Paracelsus Medical University |
| Salzburg |
| 5020 |
| Austria |
| D014947 | Wounds and Injuries |