Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Prolonged sitting has been shown to effect the response to a high fat tolerance test (HFTT) after acute exercise. This study will evaluate the effect of prolonged sitting on response to a HFTT after a short term training period.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sitting with Exercise | Active Comparator | Subjects will complete a short term training protocol while sitting >11 hours per day. This training will be preceded by a VO2max test to aid in setting the correct intensity for training. Subjects will be asked to complete three high fat tolerance tests. One to establish a baseline, the second to determine the acute effects of training, and a third at the completion of training to determine the cumulative effect of exercise training. |
|
| Walking with exercise | Active Comparator | Subjects will complete a short term training protocol while sitting <5 hours per day. This training will be preceded by a VO2max test to aid in setting the correct intensity for training. Subjects will be asked to complete three high fat tolerance tests. One to establish a baseline, the second to determine the acute effects of training, and a third at the completion of training to determine the cumulative effect of exercise training. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Prolonged sitting with exercise | Behavioral | Subjects will commit to sitting more than 11 hours per day and taking less than 5000 steps per day while participating in exercise training. |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma Triglycerides | Areas under the curve for triglyceride concentration will be calculated for hourly samples from a 6-hour lipid tolerance test | 6 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma Insulin | Areas under the curve for insulin concentration will be calculated for hourly samples from a 6-hour lipid tolerance test | 6 hours |
| Plasma glucose | Areas under the curve for glucose concentration will be calculated for hourly samples from a 6-hour lipid tolerance test |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Texas at Austin Human Performance Laboratory | Austin | Texas | 78712 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34398061 | Derived | Burton HM, Wolfe AS, Vardarli E, Satiroglu R, Coyle EF. Background Inactivity Blunts Metabolic Adaptations to Intense Short-Term Training. Med Sci Sports Exerc. 2021 Sep 1;53(9):1937-1944. doi: 10.1249/MSS.0000000000002646. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D050197 | Atherosclerosis |
| D024821 | Metabolic Syndrome |
| ID | Term |
|---|---|
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
Not provided
Not provided
Subjects will be randomly assigned to either the sitting plus exercise or walking plus exercise.
Not provided
Not provided
Not provided
Not provided
| Active walking with exercise. | Behavioral | Subjects will commit to sitting less than 5 hours per day and taking more than 10000 steps per day while participating in exercise training. |
|
| 6 hours |
| D007333 |
| Insulin Resistance |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |