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Delirium is the most common neurological complication of cardiac surgery patients and associated with poor prognosis. In recent years, the important role of quantitative electroencephalogram (qEEG) in brain function monitoring is becoming increasingly prominent. The purpose of this study is to evaluate the effect of qEEG in predictive of post-operation delirium and prognosis of cardiac surgery patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Delirium Group | The cardiac surgery patients with delirium receive the quantitative electroencephalogram (qEEG) monitoring within 1 hour when they admitted to ICU |
| |
| Non-delirium Group | The cardiac surgery patients without delirium receive the quantitative electroencephalogram (qEEG) monitoring within 1 hour when they admitted to ICU |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| quantitative electroencephalogram (qEEG) | Device | the patients receive the quantitative electroencephalogram (qEEG) monitoring within 1 hour when they admitted to ICU |
|
| Measure | Description | Time Frame |
|---|---|---|
| amplitude integrated electroencephalogram (aEEG) | the electroencephalogram amplitude of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| alpha frequency band energy | the percentage of alpha frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit | 24 hours |
| beta frequency band energy |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients receiving cardiac surgery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Liu Wenxue, master | Contact | 15751866806 | diligent_hi@163.com | |
| Yang Congshan, professor | Contact | 13851462550 | ycs7415@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Liu Wenxue, master | Southeast University | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39730694 | Derived | Guo Z, Wan W, Liu W, Liu L, Yang Y, Yang C, Cui X. Quantitative electroencephalography predicts postoperative delirium in adult cardiac surgical patients from a prospective observational study. Sci Rep. 2024 Dec 28;14(1):31101. doi: 10.1038/s41598-024-82422-7. |
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| ID | Term |
|---|---|
| D003693 | Delirium |
| ID | Term |
|---|---|
| D003221 | Confusion |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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the percentage of beta frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit
| 24 hours |
| theta frequency band energy | the percentage of theta frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit | 24 hours |
| delta frequency band energy | the percentage of delta frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit | 24 hours |
| alpha variability | the variability of alpha frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit | 24 hours |
| arterial oxygen saturation (SaO2) | the level of arterial oxygen saturation (SaO2) of cardiac surgery patients when admitted to intensive care unit | 24 hours |
| central venous oxygen saturation (ScvO2) | the level of central venous oxygen saturation(ScvO2) of cardiac surgery patients when admitted to intensive care unit | 24 hours |
| neuron specific enolase (NSE) | the level of neuron specific enolase (NSE) of cardiac surgery patients when admitted to intensive care unit | 24 hours |
| interleukin-6 (IL-6) | the level of interleukin-6 (IL-6) of cardiac surgery patients when admitted to intensive care unit | 24 hours |
| troponin i (TNI) | the level of troponin i (TNI) of cardiac surgery patients when admitted to intensive care unit | 24 hours |
| high-sensitivity C-reactive protein (hs-CRP) | the level of high-sensitivity C-reactive protein (hs-CRP) of cardiac surgery patients when admitted to intensive care unit | 24 hours |
| N-terminal pro brain natriuretic peptide (NT-pro-BNP) | the level of N-terminal pro brain natriuretic peptide (NT-pro-BNP) of cardiac surgery patients when admitted to intensive care unit | 24 hours |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |