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| Name | Class |
|---|---|
| Mbarara University of Science and Technology | OTHER |
| Harvard School of Public Health (HSPH) | OTHER |
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This study evaluates the impact of a solar lighting system on kerosene lamp use, levels of indoor air pollution, and health in women living in rural Uganda. Half of the participants will receive the lighting systems immediately, while the other half will receive them after an 18 month delay.
One fifth of the global population relies on kerosene lamps for lighting, yet few studies have focused on kerosene lighting as a source of indoor air pollution. In our preliminary studies performed in Uganda, we show that homes using solar lighting have much lower levels of indoor air pollution compared to homes using kerosene lighting. The primary goal of this study is to determine the extent to which solar lighting will reduce kerosene use and indoor air pollution in rural Uganda, whether this intervention improves lung health, and to identify the role bacteria in our gut have on determining whether or not people will get sick from indoor air pollution.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control (usual lighting) | No Intervention | Participants will continue to use their usual lighting sources. | |
| Intervention (solar lighting) | Experimental | Participants will receive an indoor solar lighting system |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Solar lighting system | Other | consisting of a solar panel, rechargeable lead acid battery, charge controller, wiring and switches to 4 lighting points fitted with LED bulbs. This system will include a two-year service warranty. |
| Measure | Description | Time Frame |
|---|---|---|
| Fine particulate matter (PM2.5) and Black Carbon | Sampling for PM2.5 and Black Carbon over 48 hours will be collected | 48 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Daily use of solar lighting system (hours per day) | A current monitory is installed as part of the solar lighting system that measures the hours per day each light switch is turned on | baseline, 3 months, 6 months, 12 months after the intervention |
| Blood pressure |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Peggy S Lai, MD MPH | Massachusetts General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | ||
| Mbarara University of Science and Technology |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42148043 | Derived | Huang CY, Nuwagira E, Tisza M, Kim M, Tayebwa M, Vieira J, Lam N, Wallach E, Wiens M, Tsai AC, Valeri L, Vallarino J, Allen JG, Lai PS. Effect of Household Air Pollution on the Gut Microbiome and Virome of Adult Women Living in Uganda. Environ Health Perspect. 2026 Apr 17;134(1):75-90. doi: 10.1021/EHP.6c00064. eCollection 2026 May 5. | |
| 37052216 |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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Randomization will be performed using dummy codes to represent intervention and control groups by an independent statistician; blinding of the intervention to the participants and field team is not possible, but data analysis will take place prior to unblinding.
Resting blood pressure |
| baseline, 3 months, 6 months, 12 months after the intervention |
| Forced Expiratory Volume in one Second (FEV1) | Pre- and Post- bronchodilator spirometry | baseline, 3 months, 6 months, 12 months after the intervention |
| Heart rate variability | Resting 10 minute heart rate variability | baseline, 3 months, 6 months, 12 months after the intervention |
| Stool microbiome | Microbial sequencing of the stool will be performed | baseline, 3 months, 6 months, 12 months after the intervention |
| Qualitative interviews | 1:1 qualitative interviews will be performed with participants | Post-intervention |
| Respiratory symptoms | Presence/absence of respiratory symptoms based on the American Thoracic Society Respiratory Disease questionnaire | baseline, 3 months, 6 months, 12 months after intervention |
| Mbarara |
| Uganda |
| Ponticiello M, Nuwagira E, Tayebwa M, Mugerwa J, Nahabwe H, Nakasita C, Tumuhimbise JB, Lam NL, Wiens MO, Vallarino J, Allen JG, Muyanja D, Tsai AC, Sundararajan R, Lai PS. "If you have light, your heart will be at peace": A qualitative study of household lighting and social integration in southwestern Uganda. J Glob Health. 2023 Apr 14;13:04026. doi: 10.7189/jogh.13.04026. |
| 35225388 | Derived | Wallach ES, Lam NL, Nuwagira E, Muyanja D, Tayebwa M, Valeri L, Tsai AC, Vallarino J, Allen JG, Lai PS. Effect of a solar lighting intervention on fuel-based lighting use and exposure to household air pollution in rural Uganda: A randomized controlled trial. Indoor Air. 2022 Feb;32(2):e12986. doi: 10.1111/ina.12986. |