Pharmacokinetics of Tacrolimus in Children

Population Pharmacokinetics of Tacrolimus in Children With Nephrotic Syndrome

the present study was conducted to assess the population pharmacokinetics of tacrolimus in children with nephrotic syndrome and to use these data to calculate an optimal dosing regimen of tacrolimus for use in these patients.

Inclusion Criteria:

• patients have been diagnosed with nephrotic syndrome;
• age range: 1 month to 18 years old
• tacrolimus used as part of regular treatment

Exclusion Criteria:

• expected survival time less than the treatment cycle;
• patients with other factors that researcher considers unsuitable for inclusion.