Predictors for Recurrence of Atrial Fibrillation After Electrical Cardioversion

Predictors for Recurrence of Atrial Fibrillation After Electrical Cardioversion

In patients with persistent atrial fibrillation (AF), electrical cardioversion is very effective in restoring sinus rhythm if modern, biphasic cardioverters are used. However, approximately 50 per cent of the successfully cardioverted patients experience a recurrence of AF within a few weeks. Therefore, valid predictors for AF recurrence would be of great clinical relevance, to avoid unnecessary procedures.

In the PRE-ELECTRIC study, we will investigate the predictive value of potential new biomarkers with respect to AF recurrence within 30 days after electrical cardioversion. We will investigate serum and plasma biomarkers, electrocardiological markers and echocardiographic variables in this respect. The study will be undertaken as a prospective cohort study at Bærum Hospital, Vestre Viken Hospital Trust, with national and international collaborators.

Inclusion Criteria:

• Patients > 18 years referred for electrical cardioversion for persistent atrial fibrillation
• Signed, informed consent

Exclusion Criteria:

• Patients < 18 years
• Patients with paroxysmal atrial fibrillation
• Patients unwilling to participate or without consent competence