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Although aortic valve replacement is recommended for any symptomatic severe calcific aortic stenosis, the therapeutic decision may be difficult. because of patient age and comorbidities.
Transcatheter Aortic Valve Implantation (TAVI) has recently extended the therapeutic indications in patients at high risk of surgery. However, the proportion of different treatments is not known in a contemporary population that can be treated according to the different resources currently available.
The scientific goal of this observational research is to evaluate intra-hospital therapeutic decision in elderly patients referred because of symptomatic severe aortic stenosis.
The one-year survival will be analyzed according to the therapeutic decision and the characteristics of the patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hospitalized patients due to a severe, symptomatic aortic sten | Patients who agreed to participate in the study, aged ≥75 years, with severe and symptomatic aortic stenosis, and hospitalized in one of the medical and surgical centers participating in the study |
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| Measure | Description | Time Frame |
|---|---|---|
| Collate the therapeutic decision (medical treatment, TAVI [Transcatheter Aortic Valve Implantation] or surgical aortic valve replacement) comprehensively for all hospitalized patients because of a severe, symptomatic RAC. | The primary endpoint is the therapeutic indication retained by the medical-surgical team in charge of the patient during hospitalization: medical treatment, TAVI or surgical aortic valve replacement. | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| 1 year-survival | Survival at one year will be analyzed. The analysis of the relationship between therapeutic decision and survival will be studied by taking surgical aortic valve replacement as a reference class. | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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Multicenter study to prospectively include all patients who agreed to participate in the study, with severe and symptomatic aortic stenosis, and hospitalized in one of the medical-surgical centers participating in the study and offering all the therapeutic resources for the taking into account charge of patients with aortic stenosis
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21263455 | Background | Iung B, Vahanian A. Epidemiology of valvular heart disease in the adult. Nat Rev Cardiol. 2011 Mar;8(3):162-72. doi: 10.1038/nrcardio.2010.202. Epub 2011 Jan 25. | |
| 23143128 | Background | Iung B, Vahanian A. Degenerative calcific aortic stenosis: a natural history. Heart. 2012 Nov;98 Suppl 4:iv7-13. doi: 10.1136/heartjnl-2012-302395. |
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| ID | Term |
|---|---|
| C562942 | Aortic Valve, Calcification of |
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