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| Name | Class |
|---|---|
| M.D. Anderson Cancer Center | OTHER |
| Sichuan Cancer Hospital and Research Institute | OTHER |
| Zigong No.1 Peoples Hospital | OTHER |
| Jiangyou People's Hospital |
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Investigators propose a multicenter prospective observational cohort study to develop and validate essential technical parameters for establishing the patient-reported outcome-based perioperative symptom management cohort in patients with lung cancer. With at least 300 patients with initial diagnosis of lung cancer and scheduled for surgery, this study will administer symptom assessments (MDASI-LC) and quality of life assessments (SIQOL) before surgery (typically within 3 days before surgery), daily after surgery (in hospital ≤ 14 days), and weekly after discharge, up to 4 weeks (±3 days) or the start day of postoperative oncologic treatment. In the upgraded research protocol, symptom and quality of life assessments (every 3 month for 1 year, every 6 month for 2-3 year, every 12 month for 4-5 year), as well as the follow-up of clinical outcomes will continue until 5 years after surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lung cancer surgical patients | Patient-reported symptom assessments in patients undergoing lung cancer surgery. |
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| Measure | Description | Time Frame |
|---|---|---|
| Perioperative symptom burden (severity, freqency and impact on daily functioning) measured by MDASI-LC | We will use MD Anderson Symptom Inventory lung cancer module (MDASI-LC) to longitudinally assess the perioperative symptom burden for lung cancer patients. The symptom burden will be profiled as symptom severity, frequency of moderate to severe symptom and its interference with daily functioning. | less than 6 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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Lung cancer patients planning to undergo surgery
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| Name | Affiliation | Role |
|---|---|---|
| Xiaojun Yang, MD | Sichuan Cancer Hospital and Research Institute | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sichuan Cancer Hospital and Research Institute | Chengdu | Sichuan | 610041 | China | ||
| Chengdu Seventh People's Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40301835 | Derived | Liao J, Hu X, Wei X, Dai W, Yu H, Tian X, Wang Y, Qin Q, Xu N, Li Y, Li Q, Shi Q, Liu X. Sex-related differences in postoperative patient-reported outcomes among lung cancer patients: a multicenter cohort study. BMC Cancer. 2025 Apr 29;25(1):800. doi: 10.1186/s12885-025-14191-z. | |
| 39670353 | Derived | Wei X, Yu H, King-Kallimanis B, Liu Y, Huang L, Dai W, Yang D, Zhou X, Li Q, Shi Q. Long-Term Function Recovery Following Upper Versus Lower Lobectomy for Lung Cancer: A Multicenter Longitudinal Cohort Study. Thorac Cancer. 2025 Jan;16(1):e15505. doi: 10.1111/1759-7714.15505. Epub 2024 Dec 13. |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| UNKNOWN |
| Chengdu Third People's Hospital | UNKNOWN |
| Chengdu Seventh People's Hospital | UNKNOWN |
| Dazhu County People's Hospital | UNKNOWN |
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| Chengdu |
| Sichuan |
| China |
| Chengdu Third People's Hospital | Chengdu | Sichuan | China |
| Dazhu County People's Hospital | Dazhou | Sichuan | China |
| Jiangyou People's Hospital | Jiangyou | Sichuan | 621700 | China |
| Zigong First People's Hospital | Zigong | Sichuan | 643000 | China |
| 31662377 | Derived | Dai W, Xie S, Zhang R, Wei X, Wu C, Zhang Y, Feng W, Liao X, Mu Y, Zhou H, Cheng X, Jiang Y, He J, Li Q, Yang X, Shi Q. Developing and validating utility parameters to establish patient-reported outcome-based perioperative symptom management in patients with lung cancer: a multicentre, prospective, observational cohort study protocol. BMJ Open. 2019 Oct 28;9(10):e030726. doi: 10.1136/bmjopen-2019-030726. |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |