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alternative plan
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The relationship between anesthetic medication and postoperative major cardiac and cerebral complications will be studied using logistic regression model.
The study group try to find out if there is a connection between the use of different anesthetic methods with different narcotic drugs and postoperative major cardiac and cerebral complications.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| non-MACE | patients without major postoperative cardiac or cerebral complications |
| |
| MACE | patients with major postoperative cardiac or cerebral complications |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| inhalation or propofol ,epidural or general anesthesia, remifentanil or sufentanil | Combination Product | Different combination of opioids and anesthetics |
|
| Measure | Description | Time Frame |
|---|---|---|
| Major cardiac complication | major cardiac event | 90 days after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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patients for non-cardiac surgery under general anesthesia
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28374886 | Background | Herling SF, Dreijer B, Wrist Lam G, Thomsen T, Moller AM. Total intravenous anaesthesia versus inhalational anaesthesia for adults undergoing transabdominal robotic assisted laparoscopic surgery. Cochrane Database Syst Rev. 2017 Apr 4;4(4):CD011387. doi: 10.1002/14651858.CD011387.pub2. | |
| 20573633 | Background |
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| ID | Term |
|---|---|
| D001239 | Inhalation |
| D000768 | Anesthesia, General |
| D000077208 | Remifentanil |
| D017409 | Sufentanil |
| ID | Term |
|---|---|
| D015656 | Respiratory Mechanics |
| D012119 | Respiration |
| D012143 | Respiratory Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |
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| Flier S, Post J, Concepcion AN, Kappen TH, Kalkman CJ, Buhre WF. Influence of propofol-opioid vs isoflurane-opioid anaesthesia on postoperative troponin release in patients undergoing coronary artery bypass grafting. Br J Anaesth. 2010 Aug;105(2):122-30. doi: 10.1093/bja/aeq111. Epub 2010 Jun 23. |
| 27054364 | Background | Min JJ, Kim G, Lee JH, Hong KY, Kim WS, Lee YT. Does the Type of Anesthetic Technique Affect In-Hospital and One-Year Outcomes after Off-Pump Coronary Arterial Bypass Surgery? PLoS One. 2016 Apr 7;11(4):e0152060. doi: 10.1371/journal.pone.0152060. eCollection 2016. |
| 25618118 | Background | Guclu CY, Unver S, Aydinli B, Kazanci D, Dilber E, Ozgok A. The effect of sevoflurane vs. TIVA on cerebral oxygen saturation during cardiopulmonary bypass--randomized trial. Adv Clin Exp Med. 2014 Nov-Dec;23(6):919-24. doi: 10.17219/acem/37339. |
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
| D011422 | Propionates |
| D000144 | Acids, Acyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
| D010880 | Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D005283 | Fentanyl |