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The purpose of this study is to investigate the effect of different kinds of popular peripheral nerve blocks for postoperative analgesia after cesarean delivery is completed, compared with traditional epidual analgesia.
Visual Analogue Scale (VAS) and morphine consumption was adopted to evaluate the pain relief.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| QLB type 2 | Experimental | Ultrasound-guided, Inject at the point posterior to quadratus lumborum muscle, 0.2% ropivacaine 30mL in each side for a total of 60mL. Subjects also receive an intravenous patient controlled analgesia (PCA) pump of 0.5 mg/mL morphine for 48 hours. |
|
| QLB type 3 | Experimental | Ultrasound-guided, Inject at the point between the quadratus lumborum and the psoas major muscle, 0.2% ropivacaine 30mL in each side for a total of 60mL. Subjects also receive an intravenous patient controlled analgesia (PCA) pump of 0.5 mg/mL morphine for 48 hours. |
|
| QLB type 2+3 | Experimental | Ultrasound-guided, conduct both QLB type 2 and 3, 0.2% ropivacaine 15mL in each point of injection, for a total of 60mL. Subjects also receive an intravenous patient controlled analgesia (PCA) pump of 0.5 mg/mL morphine for 48 hours. |
|
| epidural anesthesia group (EA) | Active Comparator | Epidural catheter placement was conducted when finishing spinal anesthesia. After surgery, 30 mL saline (placebo) was Injected at the point posterior to the quadratus lumborum in each side for a total of 60mL. We used a single bolus of 0.15% ropivacaine + 2 mg morphine (diluted in 6 ml saline) via epidural cathether. Subjects also receive an intravenous patient controlled analgesia (PCA) pump of 0.5 mg/mL morphine for 48 hours. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| QLB | Procedure | QLB, quadratus lumborum block. |
|
| Measure | Description | Time Frame |
|---|---|---|
| the change trend of Visual Analogue Scale (VAS) at rest and movement | The purpose is to view the change of the level of pain assessed by subjects at adjacent time points. We would set 0, 4, 6, 12, 24, 48 hours postoperatively as observational time points. | 0-48 hours postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| total morphine consumption | total morphine consumption | 0-48 hours postoperatively |
| complications | nausea, vomiting, retention of urine, lower limb weakness, etc. |
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Inclusion Criteria:
Exclusion Criteria:
Subjects undergo cesarean delivery
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The First Affiliated Hospital of Sun Yat-Sen University | Guangzhou | Guangdong | 510080 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26225500 | Background | Blanco R, Ansari T, Girgis E. Quadratus lumborum block for postoperative pain after caesarean section: A randomised controlled trial. Eur J Anaesthesiol. 2015 Nov;32(11):812-8. doi: 10.1097/EJA.0000000000000299. |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| ID | Term |
|---|---|
| D016058 | Analgesia, Patient-Controlled |
| ID | Term |
|---|---|
| D000698 | Analgesia |
| D000760 | Anesthesia and Analgesia |
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|
| Intravenous patient controlled analgesia (PCA) | Procedure | Intravenous patient controlled analgesia (PCA) pump was used to supply additional analgesia and removed 48 h post-operationally. |
|
| 0-48 hours postoperatively |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |