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The researchers investigated the anti-diabetic effects of Allium hookeri root extract for Korean prediabetic participants.
Allium hookeri root is widely consumed as a vegetable and herbal medicine in Asia. Although the antidiabetic activities of Allium hookeri have been documented in animal studies, the improved effects of Allium hookeri on human are not clear. Therefore, in this study, the researchers investigated whether Allium hookeri root extract could be effective in reducing the risk of type 2 diabetes in individuals with prediabetes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Allium hookeri extract | Experimental | take two capsules per day (486 mg/day) for 8 weeks |
|
| Placebo | Placebo Comparator | take two capsules per day for 8 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Allium hookeri extract | Dietary Supplement | take two capsules per day (486 mg/day) for 8 weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes of blood glucose during OGTT | Changes of fasting and postprandial glucose during OGTT were assessed before and after the intervention | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Changes of blood insulin | Changes of blood insulin were assessed before and after the intervention | 8 week |
| Changes of C-peptide | Changes of C-peptide were assessed before and after the intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32631388 | Derived | Park SH, Bae UJ, Choi EK, Jung SJ, Lee SH, Yang JH, Kim YS, Jeong DY, Kim HJ, Park BH, Chae SW. A randomized, double-blind, placebo-controlled crossover clinical trial to evaluate the anti-diabetic effects of Allium hookeri extract in the subjects with prediabetes. BMC Complement Med Ther. 2020 Jul 6;20(1):211. doi: 10.1186/s12906-020-03005-3. |
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| ID | Term |
|---|---|
| D011236 | Prediabetic State |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| Placebo | Dietary Supplement | take two capsules per day |
|
| 8 week |
| Changes of HbA1c | Changes of HbA1c were assessed before and after the intervention | 8 week |
| D004700 | Endocrine System Diseases |