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The pronostic value of Circulating Tumoral Cells(CTC) 's dosage by the method ISET® (tumoral cell isolation by size) in patients with bronchial cancer was previously demonstrated.
However, no kinetic study was ever realized to study the value of the CTC as predictive indicator of answer to the therapy. This project plans to study patients in an early stage and patients at advance stage locally moved forward or metastatic of the disease by evaluation of the presence and the number of CTC before every cure. This collaborative and original study should allow to refine the diagnoses of answer and to plan the possible relapses what would allow a premature institution of the treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| early stage bronchial cancer | Other | Early stage which can benefit from a surgical resection. A taking will be made in preoperative then in every consultation of follow-up after the intervention |
|
| advanced stage bronchial cancer | Other | Patients locally moved forward or at a metastatic stage handled by chemotherapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ISET® - Isolation by Size of Tumor cells | Diagnostic Test | early stage bronchial cancer patient will have a blood collection |
|
| Measure | Description | Time Frame |
|---|---|---|
| numeration of CTC (circulant tumoral cell) | Day 1 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jean P Tredaniel, Pr | Fondation Hôpital Saint-Joseph | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Groupe Hospitalier Paris Saint Joseph | Paris | Île-de-France Region | 75014 | France |
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| ID | Term |
|---|---|
| D002283 | Carcinoma, Bronchogenic |
| ID | Term |
|---|---|
| D001984 | Bronchial Neoplasms |
| D008175 | Lung Neoplasms |
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
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| ISET® - Isolation by Size of Tumor cells | Diagnostic Test | advanced stage bronchial cancer patient will have a blood collection |
|
| D009371 |
| Neoplasms by Site |
| D009369 | Neoplasms |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |