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| ID | Type | Description | Link |
|---|---|---|---|
| NCI-2018-01276 | Registry Identifier | NCI CTRP |
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The goal of this clinical research study is learn about side effects and the success of bronchoscopies when performed in cancer patients with and without symptoms.
This is an investigational study.
Up to 110 patients will take part in this study. All will be enrolled at MD Anderson.
If participant agrees to take part in this study, researchers will collect information from participant's medical records.
Length of Study:
Researchers will continue to collect participant's medical information for up to 2 years.
Additional Information:
Participant's data will be kept in a database on a password-protected computer in a secure office. This information will only be available to the study doctors and staff.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bronchoscopy Data Collection | Medical information collected after bronchoscopy for up to 2 years. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Medical Data Collection | Behavioral | Medical information collected after bronchoscopy for up to 2 years. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Time to Any Complication Requiring Treatment | Researchers will estimate the hazard function of time to any complications in the framework of competing risks while death is the competing risk.3 Researchers will graphically visualize the hazard function of time to any complications using Kernel smoothing method. | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Quality-Adjusted Survival | Researchers will evaluate the relationship between covariates and quality-adjusted survival. | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Early Intervention | Early intervention cases defined as those with anatomic narrowing and no or mild dyspnea (as measured by the Borg score). | 2 years |
| Late Intervention | Late intervention cases defined as those with moderate or severe dyspnea due to airway narrowing. |
Inclusion Criteria:
° All patients undergoing interventional bronchoscopy during the first 12 months will be enrolled, with follow-up occurring out to 2 years from the study startup (the duration of the grant).
Exclusion Criteria:
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Participants scheduled for standard of care bronchoscopy at UT MD Anderson Cancer Center in Houston, Texas.
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| Name | Affiliation | Role |
|---|---|---|
| David Ost, MD | M.D. Anderson Cancer Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30254139 | Derived | Ong P, Grosu HB, Debiane L, Casal RF, Eapen GA, Jimenez CA, Noor L, Ost DE. Long-term quality-adjusted survival following therapeutic bronchoscopy for malignant central airway obstruction. Thorax. 2019 Feb;74(2):141-156. doi: 10.1136/thoraxjnl-2018-211521. Epub 2018 Sep 25. |
| Label | URL |
|---|---|
| University of Texas MD Anderson Cancer Center Website | View source |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| 2 years |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |