Preemptive Analgesia for Primary Dysmenorrhoea

Preemptive Analgesia for Primary Dysmenorrhoea: a Randomized Controlled Trial

Preemptive analgesia before the release of pain mediators

spasmodic dysmenorrhea is one of the most distressing symptoms in women. adolescents shows a usual absence from school . prostaglandin release is one of the most accepted theory responsible for spasmodic dysmenorrhea.

Non steroidal anti inflammatory Drugs were proved to be one of the alternative medications for spasmodic dysmenorrhea.

Getting the idea of what is called preemptive anesthesia by blocking the receptors before catching pain mediators the study participants will be divided randomly into 2 group group 1 receiving ttt 2 days before the anticipated menstruation and group 2 receiving ttt only during menstruation as analgesia

Inclusion Criteria:

• nulliparous ladies
• with regular menstrual cycle pattern
• those experienced history of dysmenorrhea (primary or spasmodic)
• patients able to sallow tables

Exclusion Criteria:

• irregular cycles
• any associated local causes( pelvic infection, endometriosis, fibroid or others)
• patients with familial Mediterranean fever or other intermenstrual attacks of abdominal pain
• gastric or duodenal ulcers or gastritis
• other contraindications to non steroidal anti-inflammatory drugs
• patients with severe diminution of vision or color discrimination
• patients with any depressive or mood disorders
• patients receiving any hormonal treatment