Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Koç University | OTHER |
Not provided
Not provided
Not provided
Not provided
Effect Mechanism Investigation of a Wearable Electrostimulator for Rapid Alleviation of Parkinson's Disease Symptoms
Activation levels of interested regions of the brain will be measured through fMRI technique prior and after the dry needling and active stimulation applications.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Active Stimulation | Active Comparator | Acupuncture needles will be inserted into the auricular zones and electrical stimulation will be given for 20 minutes. |
|
| Dry Needling | Other | Acupuncture needles will be inserted into the auricular zones for 20 minutes. However, no electrical stimulation will be given |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electrical Stimulation | Device | Percutaneous electrical nerve stimulation |
| |
| Measure | Description | Time Frame |
|---|---|---|
| fMRI - Activation level comparison of the motor and supplementary cortex | Baseline and PostStim (right after the stimulation is terminated) | |
| fMRI - Activation level comparison of the subthalamic nucleus (STN) and basal ganglia including pedunculopontine nucleus (PPN) | Baseline and PostStim (right after the stimulation is terminated) | |
| fMRI - STN, PPN and cortical connectivity alterations | Baseline and PostStim (right after the stimulation is terminated) |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Yusuf O Cakmak, Phd, MD | Otago University | Principal Investigator |
| Burak Ozsoy, PhD | Inventram | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Koc University Hospital | Istanbul | Turkey (Türkiye) |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D004558 | Electric Stimulation |
| ID | Term |
|---|---|
| D010812 | Physical Stimulation |
| D008919 | Investigative Techniques |
Not provided
Not provided
Double-blind
Not provided
Not provided
Not provided
| Dry Needling Stimulation |
| Other |
Percutaneous nerve stimulation |
|
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |