Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| Pro00088016 | Other Identifier | Duke University | |
| R01EY029885 | U.S. NIH Grant/Contract | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| National Eye Institute (NEI) | NIH |
Not provided
Not provided
Not provided
The purpose of this research study is to better understand the impact of visual impairment caused by different eye diseases on the ability to perform daily activities and compare it to that in patients without eye diseases.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Glaucoma group | Other | Patients with diagnosed glaucoma will be in the group for up to 5 years. |
|
| Suspicious of having glaucoma group | Other | Patients with suspicious of having glaucoma will be in the group for up to 5 years. |
|
| Non-glaucomatous optic neuropathies group | Other | Patients with optic neuropathies that do not look glaucomatous-like will be in the group for up to 5 years. |
|
| Age-related macular degeneration (AMD) group | Other | Patients with diagnosed age-related macular degeneration will be in the group for up to 5 years. |
|
| Retinal degenerations group | Other | Patients with other retinal degenerations excluding AMD will be in the group for up to 5 years. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Visual Performance tests | Diagnostic Test | Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Impairment Measured by Visual Functioning Test | The study team will evaluate visual impairment through a composite score of visual functioning test, ranging from 0 to 100, with lower scores indicating worse visual impairment. | 4.5 years |
| Number of Eyes Showing Progression | The number of eyes showing progression (expressed in percentage) will be compared between the home-based Brain-computer interface (BCI) testing and standard clinical testing (standard automated perimetry, SAP) | 4.5 years |
| Time to Detect Progression Measured in Years | The time to detect progression (years) will be compared between the home-based Brain-computer interface testing and standard clinical testing (standard automated perimetry). | 4.5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Standard Automated Perimetry Will be Assessed by the C-index | c-index will be calculated by the proportion of concordant pairs divided by the total number of possible evaluation pairs for progression. c-index is unitless. | 4.5 years |
| Patient-reported Quality of Life as Measured by the National Eye Institute (NEI) Visual Function Questionnaire (VFQ) 25 |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Felipe A Medeiros, MD, PhD | University of Miami | Principal Investigator |
| Henry Tseng, MD, PhD | Duke University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bascom Palmer Eye Institute | Miami | Florida | 33136 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
No patients were enrolled during the study period for groups: Non-glaucomatous optic neuropathies group; Age-related macular degeneration (AMD) group; Retinal degenerations group; Other diseases of visual pathways group.
Not provided
| ID | Title | Description |
|---|---|---|
| FG000 | Healthy Control Group | Patients labeled as healthy controls for not having any other eye diseases that would be included on the other groups will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. |
| FG001 | Glaucoma Group | Patients with diagnosed glaucoma will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. |
| FG002 | Suspicious of Having Glaucoma Group | Patients with suspicious of having glaucoma will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. |
| FG003 | Non-glaucomatous Optic Neuropathies Group | Patients with optic neuropathies that do not look glaucomatous-like will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| FG004 | Age-related Macular Degeneration (AMD) Group | Patients with diagnosed age-related macular degeneration will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| FG005 | Retinal Degenerations Group | Patients with other retinal degenerations excluding AMD will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| FG006 | Other Diseases of Visual Pathways Group | Other diseases of the visual pathway not included in the previous groups will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| Title | Milestones | Reasons Not Completed | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
|
No patients were enrolled during the study period for groups: Non-glaucomatous optic neuropathies group; Age-related macular degeneration (AMD) group; Retinal degenerations group; Other diseases of visual pathways group.
| ID | Title | Description |
|---|---|---|
| BG000 | Healthy Control Group | Patients labeled as healthy controls for not having any other eye diseases that would be included on the other groups will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Continuous | Mean |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Visual Impairment Measured by Visual Functioning Test | The study team will evaluate visual impairment through a composite score of visual functioning test, ranging from 0 to 100, with lower scores indicating worse visual impairment. | Two subjects with eyes with visual function tests with low reliability scores were excluded from the analysis. Monocular patients were included. No patients were enrolled during the study period for groups: Non-glaucomatous optic neuropathies group; Age-related macular degeneration (AMD) group; Retinal degenerations group; Other diseases of visual pathways group. | Posted | Mean | Standard Deviation | score on a scale | 4.5 years | eyes | eyes |
|
4.5 years
No patients were enrolled during the study period for groups: Non-glaucomatous optic neuropathies group; Age-related macular degeneration (AMD) group; Retinal degenerations group; Other diseases of visual pathways group.
Not provided
| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Healthy Control Group | Patients labeled as healthy controls for not having any other eye diseases that would be included on the other groups will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. |
Not provided
Not provided
No patients were enrolled during the study period for groups: Non-glaucomatous optic neuropathies group; Age-related macular degeneration (AMD) group; Retinal degenerations group; Other diseases of visual pathways group. A limited number of patients reached the 5-year follow-up mark, which did not provide enough power for progression analysis.
| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Vice Chair of Research | University of Miami | 305-326-6373 | fmedeiros@med.miami.edu |
Not provided
| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Apr 19, 2022 | Jul 2, 2024 | Prot_SAP_000.pdf |
| ICF | No | No | Yes | Informed Consent Form | Apr 19, 2022 | May 28, 2024 | ICF_001.pdf |
Not provided
| ID | Term |
|---|---|
| D005901 | Glaucoma |
| D008268 | Macular Degeneration |
| D009798 | Ocular Hypertension |
| D009901 | Optic Nerve Diseases |
| D012162 | Retinal Degeneration |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
| D012164 | Retinal Diseases |
| D003389 | Cranial Nerve Diseases |
| D009422 | Nervous System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D062207 | Brain-Computer Interfaces |
| ID | Term |
|---|---|
| D055615 | Electrical Equipment and Supplies |
| D004864 | Equipment and Supplies |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Other diseases of visual pathways group | Other | Other diseases of the visual pathway not included in the previous groups will be in the group for up to 5 years. |
|
| Healthy control group | Other | Patients labeled as healthy controls for not having any other eye diseases that would be included on the other groups will be in the group for up to 5 years. |
|
|
| Brain-computer interface | Device | The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. |
|
The scores on the NEI VFQ-25 subscale ranges from 0 to 100, with a higher score indicating greater functioning. |
| 4.5 years |
| Physician Decision |
|
| Lost to Follow-up |
|
| BG001 | Glaucoma Group | Patients with diagnosed glaucoma will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. |
| BG002 | Suspicious of Having Glaucoma Group | Patients with suspicious of having glaucoma will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. |
| BG003 | Non-glaucomatous Optic Neuropathies Group | Patients with optic neuropathies that do not look glaucomatous-like will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| BG004 | Age-related Macular Degeneration (AMD) Group | Patients with diagnosed age-related macular degeneration will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| BG005 | Retinal Degenerations Group | Patients with other retinal degenerations excluding AMD will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| BG006 | Other Diseases of Visual Pathways Group | Other diseases of the visual pathway not included in the previous groups will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| BG007 | Total | Total of all reporting groups |
| eyes |
|
| years |
| Participants |
|
| Sex: Female, Male | Count of Participants | Participants | Participants |
|
| Ethnicity (NIH/OMB) | Count of Participants | Participants | Participants |
|
| Race (NIH/OMB) | Count of Participants | Participants | Participants |
|
| OG001 | Glaucoma Group | Patients with diagnosed glaucoma will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. |
| OG002 | Suspicious of Having Glaucoma Group | Patients with suspicious of having glaucoma will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. |
| OG003 | Non-glaucomatous Optic Neuropathies Group | Patients with optic neuropathies that do not look glaucomatous-like will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| OG004 | Age-related Macular Degeneration (AMD) Group | Patients with diagnosed age-related macular degeneration will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| OG005 | Retinal Degenerations Group | Patients with other retinal degenerations excluding AMD will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
| OG006 | Other Diseases of Visual Pathways Group | Other diseases of the visual pathway not included in the previous groups will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. |
|
|
|
| Primary | Number of Eyes Showing Progression | The number of eyes showing progression (expressed in percentage) will be compared between the home-based Brain-computer interface (BCI) testing and standard clinical testing (standard automated perimetry, SAP) | Two subjects with eyes with visual function tests with low reliability scores were excluded from the analysis. Monocular patients were included. No patients were enrolled during the study period for groups: Non-glaucomatous optic neuropathies group; Age-related macular degeneration (AMD) group; Retinal degenerations group; Other diseases of visual pathways group. Healthy Control Group Arm, participants in this Arm were not assessed for this endpoint, and therefore, no data were collected. | Posted | Count of Units | eyes | 4.5 years | eyes | eyes |
|
|
|
|
| Primary | Time to Detect Progression Measured in Years | The time to detect progression (years) will be compared between the home-based Brain-computer interface testing and standard clinical testing (standard automated perimetry). | Monocular patients were included. No patients were enrolled during the study period for groups: Non-glaucomatous optic neuropathies group; Age-related macular degeneration (AMD) group; Retinal degenerations group; Other diseases of visual pathways group. Healthy Control Group Arm, participants in this Arm were not assessed for this endpoint, and therefore, no data were collected. Data collected for progressing eyes with a minimum of 1.5 years of follow-up. | Posted | Mean | Standard Deviation | years | 4.5 years | eyes | eyes |
|
|
|
| Secondary | Standard Automated Perimetry Will be Assessed by the C-index | c-index will be calculated by the proportion of concordant pairs divided by the total number of possible evaluation pairs for progression. c-index is unitless. | Two subjects with eyes with visual function tests with low reliability scores were excluded from the analysis. Monocular patients were included. No patients were enrolled during the study period for groups: Non-glaucomatous optic neuropathies group; Age-related macular degeneration (AMD) group; Retinal degenerations group; Other diseases of visual pathways group. Healthy Control Group Arm: participants in this Arm were not assessed for this endpoint, and therefore, no data were collected. | Posted | Number | unitless | 4.5 years | eyes | eyes |
|
|
|
| Secondary | Patient-reported Quality of Life as Measured by the National Eye Institute (NEI) Visual Function Questionnaire (VFQ) 25 | The scores on the NEI VFQ-25 subscale ranges from 0 to 100, with a higher score indicating greater functioning. | Subjects with questionnaires with incomplete responses were excluded from the analysis. No patients were enrolled during the study period for groups: Non-glaucomatous optic neuropathies group; Age-related macular degeneration (AMD) group; Retinal degenerations group; Other diseases of visual pathways group. | Posted | Mean | Standard Deviation | score on a scale | 4.5 years |
|
|
|
|
| 0 |
| 14 |
| 0 |
| 14 |
| 0 |
| 14 |
| EG001 | Glaucoma Group | Patients with diagnosed glaucoma will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. | 0 | 89 | 0 | 89 | 0 | 89 |
| EG002 | Suspicious of Having Glaucoma Group | Patients with suspicious of having glaucoma will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. Brain-computer interface: The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years. | 0 | 12 | 0 | 12 | 0 | 12 |
| EG003 | Non-glaucomatous Optic Neuropathies Group | Patients with optic neuropathies that do not look glaucomatous-like will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. | 0 | 0 | 0 | 0 | 0 | 0 |
| EG004 | Age-related Macular Degeneration (AMD) Group | Patients with diagnosed age-related macular degeneration will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. | 0 | 0 | 0 | 0 | 0 | 0 |
| EG005 | Retinal Degenerations Group | Patients with other retinal degenerations excluding AMD will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. | 0 | 0 | 0 | 0 | 0 | 0 |
| EG006 | Other Diseases of Visual Pathways Group | Other diseases of the visual pathway not included in the previous groups will be in the group for up to 5 years. Visual Performance tests: Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare. | 0 | 0 | 0 | 0 | 0 | 0 |
Not provided
Not provided
| D015785 |
| Eye Diseases, Hereditary |
| eyes |
|
| Progression by BCI and SAP |
|
| No progression |
|
| eyes |
|
| eyes |
|
| Other |