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In geriatric patients, there is a plethora of nutritional and illness-related parameters, resulting in a complex situation which hampers identification of risk factors.In the planned prospective study, the point and period prevalence of wound healing disorders (WHD) is examined at admission and at discharge in a cohort of 517 male and female geriatric patients. As the investigators are also interested to study the occurrence of WHD in patients with malnutrition (and other geriatric phenomena) compared to the prevalence of WHD in patients with a good nutritional Status.
The investigators will determine the prevalence of impaired wound healing upon admission to the hospital as well as the incidence of new wound healing disorders during hospital stay with specific focus on malnutrition and other important nutritional parameters in geriatric patients. Therefore the investigators intend to study consecutively admitted patients both at admission and at discharge and monitor them during hospital stay.
The investigators will investigate the associations between the individual nutritional status and body composition parameters (such as sarcopenia) and WHD in geriatric patients, taking both medical variables and the frailty syndrome into account.
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| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of wound healing disturbances | Number of wound healing disturbances upon admission to the hospital in General | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Nutritional Parameter | Mini Nutritional Assessment - Short Form (questionnaire) | Baseline and up to 3 weeks |
| Functional Parameter | Timed Up & Go Test |
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Inclusion Criteria:
Exclusion Criteria:
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Geriatric patients will be recruted upon admission to the hospital.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kristina Norman, PD Dr. | Contact | 0049/30450565139 | kristina.norman@charite.de | |
| Kristina Franz, MScIS | Contact | 0049/30450565137 | kristina.franz@charite.de |
| Name | Affiliation | Role |
|---|---|---|
| Kristina Norman, PD Dr. | Charite Research Group on Geriatrics | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Charite University Medicine, Research Group on Geriatrics | Recruiting | Berlin | 13347 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20444575 | Background | Shahin ES, Meijers JM, Schols JM, Tannen A, Halfens RJ, Dassen T. The relationship between malnutrition parameters and pressure ulcers in hospitals and nursing homes. Nutrition. 2010 Sep;26(9):886-9. doi: 10.1016/j.nut.2010.01.016. Epub 2010 May 4. |
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| ID | Term |
|---|---|
| D044342 | Malnutrition |
| D000073496 | Frailty |
| ID | Term |
|---|---|
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Baseline and up to 3 weeks |
| Functional Parameter | 4m-walk Test to measure gait speed | Baseline and up to 3 weeks |
| Functional Parameter | Lung Test to measure respiratory force | Baseline and up to 3 weeks |
| Strength Parameter | Hand grip strength | Baseline and up to 3 weeks |
| Strength Parameter | Knee extension strength | Baseline and up to 3 weeks |
| Frailty | Frailty Status according to Fried criteria | Baseline and up to 3 weeks |
| Index of quality of life | EQ-5D-5L (questionnaire) to measure quality of life | Baseline and up to 3 weeks, after 3 months and after 6 months |
| Body composition | Bioelectric impedance analysis | Baseline and up to 3 weeks |