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| Name | Class |
|---|---|
| Severance Hospital | OTHER |
| Sejong General Hospital | OTHER |
| Gachon University Gil Medical Center | OTHER |
| Ulsan University Hospital |
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This study will retrospectively review and compare clinical outcomes between left atrial appendage occlusion with dual antiplatelet therapy versus conventional antithrombotic therapy in patients with atrial fibrillation undergoing drug-eluting stent implantation.
Composite of stroke and major bleeding will be compared after adjusting those groups using inverse probability weighted model.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| LAAO with DAPT | patients with AF who underwent PCI and treated with LAAO(either ACP or Watchman) and DAPT |
| |
| Conventional antithrombotic therapy | patients with AF who underwent PCI and treated with conventional antithrombotic therapy |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ACP or Watchman | Procedure | Left atrial appnedage occlusion using ACP or Watchman |
|
| Measure | Description | Time Frame |
|---|---|---|
| Composite of stroke and major bleeding | Primary endpoint is a composite of stroke and major bleeding. Stroke is defined as ischemic cerebrovascular event included both transient ischemic attack and ischemic cerebral infarction. Major bleeding event was defined as moderate or severe bleeding according to the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries criteria. | From date of index procedure until the date of primary endpoint occur or date of last follow up, whichever came first, assessed up to 50 months |
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Inclusion Criteria:
Exclusion Criteria:
-
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patients with AF who underwent PCI
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| Name | Affiliation | Role |
|---|---|---|
| Cheol Woong Yu, MD, PhD | Korea University Anam Hospital | Principal Investigator |
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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| OTHER |
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| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |