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| ID | Type | Description | Link |
|---|---|---|---|
| 2016-A00068-43 | Registry Identifier | ANSM |
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| Name | Class |
|---|---|
| University Hospital of Saint-Etienne | OTHER |
| University of Lyon | OTHER |
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It is well established that physical activity reduces the physiological effects of ageing. Among them, the decrease of the autonomic nervous system activity (ANS) is associated with the increase of cardiovascular events and sleep disorders occurence. It has been shown that high intensity cycle training can enhance the ANS activity by 30% in people aged of 70 years old. However, such trainings were done by old athletes used to train at intensities that could not be handled by nursing home elderly. Thus, an adapted activity such as brisk walking shall be defined to make it practicable for the many in convalescent homes. The investigators hypothesize that long term brisk walking training could lead to reactivate ANS in people living in convalescent homes.
The investigators aim to compare the effects of a 9 month brisk walking training (1 time a week or 3 times a week) on the ANS of nursing home residents.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Brisk walking 1 | Experimental | 1 time a week of 9 months brisk walking |
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| Brisk walking 3 | Experimental | 3 times a week of 9 months brisk walking |
|
| Control group | No Intervention | No brisk walking session |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Brisk walking | Behavioral | Prospective randomized clinical trial with 2 intervention groups and 1 control group. |
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| Measure | Description | Time Frame |
|---|---|---|
| SDNN value | Standard deviation of all normal nocturnal RR intervals | 9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Heart rate variability parameters | Autonomic nervous system balance (RMSSD) | 9 months |
| Heart rate variability parameters | Autonomic nervous system balance (LF/HF) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| David HUPIN, MD, PhD | Contact | 0477829109 | +33 | david.hupin@chu-st-etienne.fr |
| Name | Affiliation | Role |
|---|---|---|
| David HUPIN, MD, PhD | University Hospital of Saint-Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| French Loire Mutuality | Recruiting | Saint-Etienne | 42100 | France |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| 9 months |
| Heart rate variability parameters | Autonomic nervous system balance (Ptot) | 9 months |
| Baroreflex sensitivity (BRS) | BRS slope variation measured at rest | 9 months |
| Maximum oxygen uptake (VO2max) | Cardiopulmonary exercise testing | 9 months |
| Daily physical activity | Actimetry (Actigraph-GT3X) | 9 months |
| Daily physical activity | Adult physical activity questionnaire (APAQ) | 9 months |
| Sedentary periods | Actimetry (Actigraph GT3X) | 9 months |
| Sedentary periods | Adult physical activity questionnaire (APAQ) | 9 months |
| Muscular force | Lower limbs maximum voluntary force test measured on force chair | 9 months |
| Muscular endurance | Lower limbs endurance test measured on force chair | 9 months |
| Muscular volume gains | Lower limbs muscular magnetic resonance imaging (MRI) | 9 months |
| Plasmatic dosages of inflammatory molecules | CRP | 9 months |
| Plasmatic dosages of inflammatory molecules | TNF alpha | 9 months |
| Plasmatic dosages of inflammatory molecules | IL 17 | 9 months |
| Cognitive improvements | Neuropsychological evaluation with a neuropsychologist. | 9 months |
| Quality of life | SF-36 questionnaire | 9 months |