This is a 12-week, randomized, double-blind, placebo-controlled study to evaluate the effects of scallop-derived plasmalogen on brain fatigue, body weight and changes in blood plasmalogen in obese subjects aged 20-75 years old.

Inclusion Criteria:

• Willingness to provide informed consent to participate in the study
• BMI ≥ 25 ㎏/㎡
• HbA1C ≺ 8% without antidiabetic medication in the previous 3 months
• Stable medication for 3 months prior to the enrollment, and expectedly throughout the course of study

Exclusion Criteria:

• Scallop allergy
• Symptomatic obesity, i.e., endocrinal, hypothalamic or drug-induced obesity
• Hypertension under medication with 4 or more drugs
• Hepatic disorder with AST ≥ 5 times upper limit of the normal range
• Mental disorder including schizophrenia and neurosis
• Alcohol dependence
• History of malignancy for which treatment completed in the past 5 years
• Inflammatory disease
• Use of plasmalogen supplement in the past 3 months
• Ineligible condition as determined by study physician