Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery

Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery: Comparison of Neostigmine and Sugammadex

Compare the reversal effect of neostigmine and sugammadex using quantitative neuromuscular monitoring

At the end of surgery, decide the dosage of reversal referring to quantitative neuromuscular monitoring value (TOF). After the administration of reversal, the anesthesiologist who are going to manage the participant should not check the quantitative neuromuscular monitoring and determine the timing of extubation only with his (or her) judgement. After entering post-anaesthesia care unit (PACU) measure the TOF value and check the incidence of TOF ratio > 0.9 between the neostigmine group and sugammadex group.

Inclusion Criteria:

• patients aged over 18 years, planned to undergoing elective laparoscopic surgery under general anesthesia

Exclusion Criteria:

• Obesity BMI over 30 kg/m2
• Impairment of renal or/and liver function
• Allergy to rocuronium, sugammadex
• (Familial) history of malignant hyperthermia
• Taking medicines which is affecting neuromuscular function