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The purpose of this pilot study is to determine the feasibility of at home thermal therapy with a wireless, portable device, as an effective management of Meibomian Gland Dysfunction.
This will be done by assessing patients for improvement in symptoms and ocular oil gland function after 4 weeks of a daily thermal therapy application.
This study will be a non-randomized, open label study of subjects with documented MGD. All subjects will be sent home with a wireless, portable thermal therapy device and examined pre and post treatment period. Subjects will be asked to use the device at bedtime for 5 minutes daily for 4 weeks. After treatment subjects will be re-examined and measured for clinical and symptomatic change in their MGD as well as changes to their sleep quality and anxiety index. Subjects will also be followed after treatment has been completed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Thermal Therapy | Experimental | Heat application using at home thermal therapy device |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Thermal therapy device | Device | Thermal therapy of blocked Meibomian glands |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Non-Invasive Tear Film Break Up Time (NITFBUT) in Seconds | Ocular surface analysis of tear film evaporation | Before and after 4 weeks of daily treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Ocular Surface Disease Index (OSDI) Score | Standardized symptom questionnaire | Before and after 4 weeks of daily treatment |
| Meibum Expressibility | Grade of Meibum oil expressibility from Meibomian Gland |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sharmin Habib, OD | Contact | 5875017422 | sharmin@umay.care |
| Name | Affiliation | Role |
|---|---|---|
| Hermina Strungaru, MD | University of Alberta | Principal Investigator |
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| ID | Term |
|---|---|
| D000080343 | Meibomian Gland Dysfunction |
| D015352 | Dry Eye Syndromes |
| ID | Term |
|---|---|
| D005141 | Eyelid Diseases |
| D005128 | Eye Diseases |
| D007766 | Lacrimal Apparatus Diseases |
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| Before and after 4 weeks of daily treatment |
| Sleep Quality | Pittsburg Sleep Quality Index (PSQI) | Before and after 4 weeks of daily treatment |
| State Trait and Anxiety | State-Trait Anxiety Index (STAI) | Before and after 4 weeks of daily treatment |