| Primary | Necrotising Enterocolitis - for the Enteral Nutrition Comparison | Defined according to the case definition of Battersby et al., 2017, JAMA Pediatrics | NA indicates <5 where the cell value is withheld to avoid identifying participants | Posted | | Count of Participants | | Participants | | From date of birth until date of final neonatal unit discharge, assessed up to 1 year | | | | ID | Title | Description |
|---|
| OG000 | Received Enteral (Milk) Feeds During Therapeutic Hypothermia | The gradual introduction of enteral (milk) feeds during therapeutic hypothermia:
- Included in this is any type of milk (e.g. expressed maternal breast milk, expressed donor breast milk and artificial formula)
- This health technology includes different routes of administering enteral feeds such as nasogastric tube (gavage feeding) and bottle
- This health technology also includes different rates of increasing enteral feeds (for example by 15ml/kg/day, by 30ml/kg/day or faster)
| | OG001 | Enteral (Milk) Feeds Withheld During Therapeutic Hypothermia | Withholding enteral feeds (keeping a baby nil per os) for the duration of hypothermia. | | OG002 | Received Parenteral Nutrition During Therapeutic Hypothermia: | Administration of parenteral nutrition during therapeutic hypothermia:
- Included in this are different compositions of parenteral nutrition (for example standard, pre-prepared bags of nutrition and individually tailored parenteral nutrition)
- This health technology includes different routes of administration of parenteral nutrition such as via a peripheral intravenous cannula, percutaneous central venous catheter ('long line') or umbilical venous catheter.
- This health technology also includes different volumes of parenteral nutrition (e.g. 40ml/kg/day, 60ml/kg/day or greater).
| | OG003 | Did Not Receive Parenteral Nutrition During Therapeutic Hypothermia | Received standard intravenous fluids (10% dextrose with additional electrolytes added where required) for the duration of hypothermia. |
| | Units | Counts |
|---|
| Participants | - OG0001618
- OG0011618
- OG0021240
- OG003
|
| | Title | Denominators | Categories |
|---|
| | | Title | Measurements |
|---|
| - OG000NANA indicates \<5 where the cell value is withheld to avoid identifying participants
- OG001NANA indicates \<5 where the cell value is withheld to avoid identifying participants
- OG002NA
|
|
| |
| Primary | Blood Stream Infection - for the Parenteral Nutrition Comparison | defined according to the Healthcare Quality Improvement Partnership (HQIP) National Neonatal Audit Programme (NNAP) case definition: pure growth of a recognised pathogen from a normally sterile site | | Posted | | Count of Participants | | Participants | | From date of birth until date of final neonatal unit discharge, assessed up to 1 year | | | | ID | Title | Description |
|---|
| OG000 | Received Enteral (Milk) Feeds During Therapeutic Hypothermia | The gradual introduction of enteral (milk) feeds during therapeutic hypothermia:
- Included in this is any type of milk (e.g. expressed maternal breast milk, expressed donor breast milk and artificial formula)
- This health technology includes different routes of administering enteral feeds such as nasogastric tube (gavage feeding) and bottle
- This health technology also includes different rates of increasing enteral feeds (for example by 15ml/kg/day, by 30ml/kg/day or faster)
| | OG001 | Enteral (Milk) Feeds Withheld During Therapeutic Hypothermia | Withholding enteral feeds (keeping a baby nil per os) for the duration of hypothermia. | | OG002 | Received Parenteral Nutrition During Therapeutic Hypothermia: | Administration of parenteral nutrition during therapeutic hypothermia:
- Included in this are different compositions of parenteral nutrition (for example standard, pre-prepared bags of nutrition and individually tailored parenteral nutrition)
- This health technology includes different routes of administration of parenteral nutrition such as via a peripheral intravenous cannula, percutaneous central venous catheter ('long line') or umbilical venous catheter.
- This health technology also includes different volumes of parenteral nutrition (e.g. 40ml/kg/day, 60ml/kg/day or greater).
|
|
| Secondary | Survival | Survival at neonatal unit discharge | | Posted | | Count of Participants | | Participants | | From date of birth until date of final neonatal unit discharge, assessed up to 1 year | | | | ID | Title | Description |
|---|
| OG000 | Received Enteral (Milk) Feeds During Therapeutic Hypothermia | The gradual introduction of enteral (milk) feeds during therapeutic hypothermia:
- Included in this is any type of milk (e.g. expressed maternal breast milk, expressed donor breast milk and artificial formula)
- This health technology includes different routes of administering enteral feeds such as nasogastric tube (gavage feeding) and bottle
- This health technology also includes different rates of increasing enteral feeds (for example by 15ml/kg/day, by 30ml/kg/day or faster)
| | OG001 | Enteral (Milk) Feeds Withheld During Therapeutic Hypothermia | Withholding enteral feeds (keeping a baby nil per os) for the duration of hypothermia. | | OG002 | Received Parenteral Nutrition During Therapeutic Hypothermia: | Administration of parenteral nutrition during therapeutic hypothermia:
- Included in this are different compositions of parenteral nutrition (for example standard, pre-prepared bags of nutrition and individually tailored parenteral nutrition)
- This health technology includes different routes of administration of parenteral nutrition such as via a peripheral intravenous cannula, percutaneous central venous catheter ('long line') or umbilical venous catheter.
- This health technology also includes different volumes of parenteral nutrition (e.g. 40ml/kg/day, 60ml/kg/day or greater).
|
|
| Secondary | Length of Stay | Number of days between first neonatal unit admission and final neonatal unit discharge for surviving infants | | Posted | | Mean | 95% Confidence Interval | Days | | From date of birth until date of final neonatal unit discharge, assessed up to 1 year | | | | ID | Title | Description |
|---|
| OG000 | Received Enteral (Milk) Feeds During Therapeutic Hypothermia | The gradual introduction of enteral (milk) feeds during therapeutic hypothermia:
- Included in this is any type of milk (e.g. expressed maternal breast milk, expressed donor breast milk and artificial formula)
- This health technology includes different routes of administering enteral feeds such as nasogastric tube (gavage feeding) and bottle
- This health technology also includes different rates of increasing enteral feeds (for example by 15ml/kg/day, by 30ml/kg/day or faster)
| | OG001 | Enteral (Milk) Feeds Withheld During Therapeutic Hypothermia | Withholding enteral feeds (keeping a baby nil per os) for the duration of hypothermia. | | OG002 | Received Parenteral Nutrition During Therapeutic Hypothermia: | Administration of parenteral nutrition during therapeutic hypothermia:
- Included in this are different compositions of parenteral nutrition (for example standard, pre-prepared bags of nutrition and individually tailored parenteral nutrition)
- This health technology includes different routes of administration of parenteral nutrition such as via a peripheral intravenous cannula, percutaneous central venous catheter ('long line') or umbilical venous catheter.
- This health technology also includes different volumes of parenteral nutrition (e.g. 40ml/kg/day, 60ml/kg/day or greater).
|
|
| Secondary | Breastfeeding | Any breastfeeding (suckling at the breast) at discharge | | Posted | | Count of Participants | | Participants | | At the point of final discharge from neonatal care, assessed up to 1 year | | | | ID | Title | Description |
|---|
| OG000 | Received Enteral (Milk) Feeds During Therapeutic Hypothermia | The gradual introduction of enteral (milk) feeds during therapeutic hypothermia:
- Included in this is any type of milk (e.g. expressed maternal breast milk, expressed donor breast milk and artificial formula)
- This health technology includes different routes of administering enteral feeds such as nasogastric tube (gavage feeding) and bottle
- This health technology also includes different rates of increasing enteral feeds (for example by 15ml/kg/day, by 30ml/kg/day or faster)
| | OG001 | Enteral (Milk) Feeds Withheld During Therapeutic Hypothermia | Withholding enteral feeds (keeping a baby nil per os) for the duration of hypothermia. | | OG002 | Received Parenteral Nutrition During Therapeutic Hypothermia: | Administration of parenteral nutrition during therapeutic hypothermia:
- Included in this are different compositions of parenteral nutrition (for example standard, pre-prepared bags of nutrition and individually tailored parenteral nutrition)
- This health technology includes different routes of administration of parenteral nutrition such as via a peripheral intravenous cannula, percutaneous central venous catheter ('long line') or umbilical venous catheter.
- This health technology also includes different volumes of parenteral nutrition (e.g. 40ml/kg/day, 60ml/kg/day or greater).
|
|
| Secondary | Hypoglycaemia | Any diagnosis of hypoglycaemia recorded after therapeutic hypothermia is commenced and before the final neonatal unit discharge | | Posted | | Count of Participants | | Participants | | From date of birth until date of final neonatal unit discharge, assessed up to 1 year | | | | ID | Title | Description |
|---|
| OG000 | Received Enteral (Milk) Feeds During Therapeutic Hypothermia | The gradual introduction of enteral (milk) feeds during therapeutic hypothermia:
- Included in this is any type of milk (e.g. expressed maternal breast milk, expressed donor breast milk and artificial formula)
- This health technology includes different routes of administering enteral feeds such as nasogastric tube (gavage feeding) and bottle
- This health technology also includes different rates of increasing enteral feeds (for example by 15ml/kg/day, by 30ml/kg/day or faster)
| | OG001 | Enteral (Milk) Feeds Withheld During Therapeutic Hypothermia | Withholding enteral feeds (keeping a baby nil per os) for the duration of hypothermia. | | OG002 | Received Parenteral Nutrition During Therapeutic Hypothermia: | Administration of parenteral nutrition during therapeutic hypothermia:
- Included in this are different compositions of parenteral nutrition (for example standard, pre-prepared bags of nutrition and individually tailored parenteral nutrition)
- This health technology includes different routes of administration of parenteral nutrition such as via a peripheral intravenous cannula, percutaneous central venous catheter ('long line') or umbilical venous catheter.
- This health technology also includes different volumes of parenteral nutrition (e.g. 40ml/kg/day, 60ml/kg/day or greater).
|
|
| Secondary | Duration of Central Venous Line | The number of days until an infant is recorded as not having a central venous line | | Posted | | Mean | 95% Confidence Interval | Days | | From date of birth until date of final neonatal unit discharge, assessed up to 1 year | | | | ID | Title | Description |
|---|
| OG000 | Received Enteral (Milk) Feeds During Therapeutic Hypothermia | The gradual introduction of enteral (milk) feeds during therapeutic hypothermia:
- Included in this is any type of milk (e.g. expressed maternal breast milk, expressed donor breast milk and artificial formula)
- This health technology includes different routes of administering enteral feeds such as nasogastric tube (gavage feeding) and bottle
- This health technology also includes different rates of increasing enteral feeds (for example by 15ml/kg/day, by 30ml/kg/day or faster)
| | OG001 | Enteral (Milk) Feeds Withheld During Therapeutic Hypothermia | Withholding enteral feeds (keeping a baby nil per os) for the duration of hypothermia. | | OG002 | Received Parenteral Nutrition During Therapeutic Hypothermia: | Administration of parenteral nutrition during therapeutic hypothermia:
- Included in this are different compositions of parenteral nutrition (for example standard, pre-prepared bags of nutrition and individually tailored parenteral nutrition)
- This health technology includes different routes of administration of parenteral nutrition such as via a peripheral intravenous cannula, percutaneous central venous catheter ('long line') or umbilical venous catheter.
- This health technology also includes different volumes of parenteral nutrition (e.g. 40ml/kg/day, 60ml/kg/day or greater).
|
|
| Secondary | Growth | Weight for post-menstrual age standard deviation score at final neonatal unit discharge. Standard deviation score, higher score means higher growth (higher weight for gestational age) | | Posted | | Mean | 95% Confidence Interval | Standard deviation score | | From date of birth until date of final neonatal unit discharge, assessed up to 1 year | | | | ID | Title | Description |
|---|
| OG000 | Received Enteral (Milk) Feeds During Therapeutic Hypothermia | The gradual introduction of enteral (milk) feeds during therapeutic hypothermia:
- Included in this is any type of milk (e.g. expressed maternal breast milk, expressed donor breast milk and artificial formula)
- This health technology includes different routes of administering enteral feeds such as nasogastric tube (gavage feeding) and bottle
- This health technology also includes different rates of increasing enteral feeds (for example by 15ml/kg/day, by 30ml/kg/day or faster)
| | OG001 | Enteral (Milk) Feeds Withheld During Therapeutic Hypothermia | Withholding enteral feeds (keeping a baby nil per os) for the duration of hypothermia. | | OG002 | Received Parenteral Nutrition During Therapeutic Hypothermia: | Administration of parenteral nutrition during therapeutic hypothermia:
- Included in this are different compositions of parenteral nutrition (for example standard, pre-prepared bags of nutrition and individually tailored parenteral nutrition)
- This health technology includes different routes of administration of parenteral nutrition such as via a peripheral intravenous cannula, percutaneous central venous catheter ('long line') or umbilical venous catheter.
- This health technology also includes different volumes of parenteral nutrition (e.g. 40ml/kg/day, 60ml/kg/day or greater).
|
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