Management of Sub-Clinical Bacteriuria in Pregnancy

Management of Sub-Clinical Bacteriuria in Pregnancy: A Feasibility Trial

The purpose of the study is to determine if treatment of pregnant women with urine cultures with a low level of bacteria (less than 100,000 colony forming units (CFU)) may decrease adverse pregnancy outcomes.

Inclusion Criteria:

• Pregnant women who seek prenatal care within the University of Texas Health System with UT Physicians.
• Urine culture of less than 100,000 CFU

Exclusion Criteria:

• Less than 18 years of age
• Risk factors to complicated UTI (including but not limited to: diverticula, urolithiasis, renal cysts, indwelling catheter, intermittent catheterization, stent placements, nephrostomy tubes, neurogenic bladder, cystocele, vesicoureteral reflux, ileal conduit)
• Use of immunosuppressant drugs
• Abnormalities of the urinary tract (including but not limited to: known ureteric or urethral strictures, tumors of the urinary tract, pelvicalyceal obstruction, congenital anomalies, history of urological procedures)
• History of renal disease including renal failure and transplants
• Urine culture > 100,000 CFU of any organism